Detalhe da pesquisa
1.
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
EMBO J
; 39(21): e105111, 2020 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32945574
2.
Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors.
Proc Natl Acad Sci U S A
; 114(24): 6406-6411, 2017 06 13.
Artigo
Inglês
| MEDLINE | ID: mdl-28484005
3.
How the evolution of multicellularity set the stage for cancer.
Br J Cancer
; 118(2): 145-152, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29337961
4.
Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular origins.
Genome Biol
; 25(1): 110, 2024 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38685127
5.
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments.
Nat Commun
; 14(1): 2697, 2023 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37188662
6.
Cystathionine-ß-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation.
Elife
; 112022 06 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35758651
7.
A functional genetic screen defines the AKT-induced senescence signaling network.
Cell Death Differ
; 27(2): 725-741, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31285545
8.
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Nat Commun
; 11(1): 2641, 2020 05 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32457376
9.
Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer.
Elife
; 82019 02 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30803482
10.
The 2023 generation.
Nat Cancer
; 4(12): 1630-1635, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38102362