Detalhe da pesquisa
1.
Enzymatic assembly of the salinosporamide γ-lactam-ß-lactone anticancer warhead.
Nat Chem Biol
; 18(5): 538-546, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35314816
2.
Early use of nitazoxanide in mild COVID-19 disease: randomised, placebo-controlled trial.
Eur Respir J
; 58(1)2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33361100
3.
Natural allosteric modulators and their biological targets: molecular signatures and mechanisms.
Nat Prod Rep
; 37(4): 488-514, 2020 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32048675
4.
Water-Soluble Glutamic Acid Derivatives Produced in Culture by Penicillium solitum IS1-A from King George Island, Maritime Antarctica.
J Nat Prod
; 83(1): 55-65, 2020 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31895573
5.
Formal Total Synthesis of Actinoranone: Synthesis Approaches and Cytotoxic Studies.
J Org Chem
; 83(9): 5160-5176, 2018 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29644851
6.
Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth.
J Nat Prod
; 81(10): 2296-2300, 2018 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30281303
7.
Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg Med Chem
; 23(15): 4462-4471, 2015 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26117648
8.
Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis.
J Struct Biol
; 180(1): 143-53, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22842046
9.
Initial crystallographic studies of a small heat-shock protein from Xylella fastidiosa.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 5): 535-9, 2012 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22691782
10.
Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds.
Virulence
; 13(1): 1031-1048, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35734825
11.
The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J Struct Biol
; 173(2): 323-32, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20937391
12.
Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses.
Nat Commun
; 12(1): 3038, 2021 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34031424
13.
Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J Struct Biol
; 170(3): 522-31, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20211733
14.
Biochemical alterations in caged Nile tilapia Oreochromis niloticus.
Ecotoxicol Environ Saf
; 73(5): 864-72, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20346509
15.
Antifungal compounds with anticancer potential from Trichoderma sp. P8BDA1F1, an endophytic fungus from Begonia venosa.
Braz J Microbiol
; 51(3): 989-997, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-32333271
16.
The Tripod for Bacterial Natural Product Discovery: Genome Mining, Silent Pathway Induction, and Mass Spectrometry-Based Molecular Networking.
mSystems
; 3(2)2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29629418
17.
Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.
Anticancer Agents Med Chem
; 17(13): 1777-1785, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28403779
18.
Antioxidant status and stress proteins in the gills of the brown mussel Perna perna exposed to zinc.
Chem Biol Interact
; 160(3): 232-40, 2006 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16564039
19.
Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues.
Eur J Med Chem
; 97: 42-54, 2015 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25938987
20.
Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem Biol
; 21(6): 782-91, 2014 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-24930969