Detalhe da pesquisa
1.
Towards a quantitative framework for the prediction of DDIs arising from cytochrome P450 induction.
Curr Drug Metab
; 10(4): 420-32, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19519348
2.
Modified-release hydrocortisone for circadian therapy: a proof-of-principle study in dexamethasone-suppressed normal volunteers.
Clin Endocrinol (Oxf)
; 68(1): 130-5, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-17803699
3.
Development and applications of a physiologically-based model of paediatric oral drug absorption.
Eur J Pharm Sci
; 115: 57-67, 2018 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29309876
4.
A critical evaluation of the experimental design of studies of mechanism based enzyme inhibition, with implications for in vitro-in vivo extrapolation.
Curr Drug Metab
; 7(3): 315-34, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16611025
5.
Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.
Eur J Pharm Sci
; 88: 70-82, 2016 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27019345
6.
The use of tolbutamide-induced hypoglycemia to examine the intraislet role of insulin in mediating glucagon release in normal humans.
J Clin Endocrinol Metab
; 82(5): 1458-61, 1997 May.
Artigo
Inglês
| MEDLINE | ID: mdl-9141533
7.
In-vivo indices of enzyme activity: the effect of renal impairment on the assessment of CYP2D6 activity.
Pharmacogenetics
; 9(3): 277-86, 1999 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-10471059
8.
Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment.
Pharmacogenetics
; 6(2): 121-49, 1996 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-9156692
9.
Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease.
Pharmacogenetics
; 8(3): 227-38, 1998 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-9682268
10.
Beeturia and the biological fate of beetroot pigments.
Pharmacogenetics
; 3(6): 302-11, 1993 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-8148871
11.
Debrisoquine and metoprolol oxidation in Zambians: a population study.
Pharmacogenetics
; 3(4): 205-8, 1993 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-8220440
12.
Evidence for a dissociation in the control of sparteine, debrisoquine and metoprolol metabolism in Nigerians.
Pharmacogenetics
; 2(2): 89-92, 1992 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-1302046
13.
Polymorphic debrisoquine 4-hydroxylase activity in the rat is due to differences in CYP2D2 expression.
Pharmacogenetics
; 9(3): 357-66, 1999 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-10471068
14.
In-vitro analysis of the contribution of CYP2D6.35 to ultra-rapid metabolism.
Pharmacogenetics
; 11(8): 739-41, 2001 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-11692084
15.
Systemic availability of orally administered meperidine.
Clin Pharmacol Ther
; 20(5): 535-40, 1976 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-975724
16.
Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin.
Clin Pharmacol Ther
; 32(3): 295-302, 1982 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-7105620
17.
Meperidine kinetics in man. Intravenous injection in surgical patients and volunteers.
Clin Pharmacol Ther
; 17(1): 21-30, 1975 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-1091390
18.
Metoprolol and debrisoquin metabolism in Nigerians: lack of evidence for polymorphic oxidation.
Clin Pharmacol Ther
; 40(4): 387-94, 1986 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-3757401
19.
Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers.
Clin Pharmacol Ther
; 34(6): 732-7, 1983 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-6641087
20.
Clinical pharmacokinetics of local anaesthetics.
Clin Pharmacokinet
; 4(4): 241-78, 1979.
Artigo
Inglês
| MEDLINE | ID: mdl-385208