Detalhe da pesquisa
1.
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Cell
; 171(3): 628-641.e26, 2017 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29053969
2.
Ferroptosis of tumour neutrophils causes immune suppression in cancer.
Nature
; 612(7939): 338-346, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36385526
3.
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Proc Natl Acad Sci U S A
; 120(25): e2218896120, 2023 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37327313
4.
Fatty acid transport protein 2 reprograms neutrophils in cancer.
Nature
; 569(7754): 73-78, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30996346
5.
Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury.
Proc Natl Acad Sci U S A
; 119(10): e2111537119, 2022 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35238643
6.
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.
Angew Chem Int Ed Engl
; 63(9): e202314710, 2024 Feb 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38230815
7.
Phospholipase iPLA2ß averts ferroptosis by eliminating a redox lipid death signal.
Nat Chem Biol
; 17(4): 465-476, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33542532
8.
PLA2G6 guards placental trophoblasts against ferroptotic injury.
Proc Natl Acad Sci U S A
; 117(44): 27319-27328, 2020 11 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33087576
9.
Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis.
Hepatology
; 73(3): 1176-1193, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32438524
10.
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death.
Nat Chem Biol
; 16(3): 278-290, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32080625
11.
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Nat Chem Biol
; 13(1): 81-90, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27842066
12.
Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE.
J Am Chem Soc
; 140(51): 17835-17839, 2018 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-30525572
13.
Known unknowns of cardiolipin signaling: The best is yet to come.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(1): 8-24, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-27498292
14.
Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.
Am J Physiol Lung Cell Mol Physiol
; 311(2): L303-16, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27233995
15.
TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis.
J Immunol
; 192(8): 3837-46, 2014 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24623132
16.
Oxidized lipids block antigen cross-presentation by dendritic cells in cancer.
J Immunol
; 192(6): 2920-31, 2014 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24554775
17.
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.
Cell Metab
; 36(4): 762-777.e9, 2024 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38309267
18.
Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression.
bioRxiv
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38798466
19.
Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production.
Oncoimmunology
; 12(1): 2192098, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36998620
20.
The lipase cofactor CGI58 controls placental lipolysis.
JCI Insight
; 8(10)2023 05 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37212279