Detalhe da pesquisa
1.
1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices.
Neuropharmacology
; 34(2): 141-7, 1995 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-7542369
2.
Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4- dicarboxylate.
Neuropharmacology
; 34(8): 843-50, 1995 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-8532165
3.
Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine.
J Med Chem
; 35(17): 3141-7, 1992 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-1507203
4.
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
J Med Chem
; 35(6): 1102-8, 1992 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-1552502
5.
Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties.
J Med Chem
; 40(4): 528-37, 1997 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-9046344
6.
Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.
J Med Chem
; 39(15): 2990-3000, 1996 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-8709133
7.
Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors.
J Med Chem
; 42(6): 1027-40, 1999 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-10090786
8.
Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid.
Bioorg Med Chem Lett
; 8(15): 1985-90, 1998 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-9873471