Detalhe da pesquisa
1.
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.
Cell
; 141(1): 178-90, 2010 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20371353
2.
IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model.
Exp Eye Res
; 207: 108608, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33930400
3.
Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 1. THR-149.
J Pharmacokinet Pharmacodyn
; 48(6): 825-836, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34302260
4.
Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy.
Diabetologia
; 63(10): 2235-2248, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32734440
5.
Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.
Glia
; 68(12): 2643-2660, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32645232
6.
The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders.
Exp Eye Res
; 180: 43-52, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30472075
7.
Neutralization of placental growth factor as a novel treatment option in diabetic retinopathy.
Exp Eye Res
; 165: 136-150, 2017 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28965804
8.
Inhibition of placental growth factor improves surgical outcome of glaucoma surgery.
J Cell Mol Med
; 17(12): 1632-43, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24118824
9.
The age factor in optic nerve regeneration: Intrinsic and extrinsic barriers hinder successful recovery in the short-living killifish.
Aging Cell
; 21(1): e13537, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34927348
10.
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline.
Trends Endocrinol Metab
; 33(1): 50-71, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34794851
11.
The role of different VEGF isoforms in scar formation after glaucoma filtration surgery.
Exp Eye Res
; 93(5): 689-99, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21907194
12.
Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration.
Prog Retin Eye Res
; 85: 100966, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33775825
13.
Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model.
Invest Ophthalmol Vis Sci
; 62(13): 18, 2021 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34677569
14.
Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium.
Curr Eye Res
; 46(8): 1166-1170, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33372561
15.
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Cell Metab
; 31(4): 862-877.e14, 2020 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32268117
16.
Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses.
Invest Ophthalmol Vis Sci
; 60(2): 807-822, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30811545
17.
The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases.
Prog Retin Eye Res
; 69: 116-136, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30385175
18.
The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease.
Curr Eye Res
; 44(8): 813-822, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31055948
19.
Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema.
J Med Chem
; 61(7): 2823-2836, 2018 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29517911
20.
The Combination of PlGF Inhibition and MMC as a Novel Anti-Scarring Strategy for Glaucoma Filtration Surgery.
Invest Ophthalmol Vis Sci
; 57(10): 4347-55, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27556218