Detalhe da pesquisa
1.
The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation.
FASEB J
; 38(2): e23413, 2024 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-38243760
2.
Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation.
FASEB J
; 37(6): e22939, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37130013
3.
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-ß pathology.
Cell Mol Life Sci
; 80(7): 178, 2023 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37306762
4.
The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors.
Pharmacol Rev
; 73(3): 1016-1049, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34233947
5.
The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis.
Int J Mol Sci
; 25(6)2024 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38542441
6.
From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions.
Acta Neuropathol
; 146(2): 283-299, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37286732
7.
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Brain Behav Immun
; 109: 1-22, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36584795
8.
Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?
Pharmacol Res
; 197: 106970, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37884069
9.
Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination.
Proc Natl Acad Sci U S A
; 117(9): 5028-5038, 2020 03 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32071226
10.
Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury.
Int J Mol Sci
; 24(9)2023 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37175842
11.
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Int J Mol Sci
; 24(2)2023 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36674804
12.
Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types.
Biophys J
; 121(14): 2693-2711, 2022 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35717559
13.
DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation.
Cell Mol Life Sci
; 78(19-20): 6631-6644, 2021 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-34482420
14.
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders.
Cell Mol Life Sci
; 78(10): 4615-4637, 2021 May.
Artigo
Inglês
| MEDLINE | ID: mdl-33751149
15.
Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation.
J Neuroinflammation
; 18(1): 255, 2021 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34740381
16.
Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner.
J Autoimmun
; 124: 102723, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34481107
17.
Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia.
Behav Pharmacol
; 32(6): 459-471, 2021 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34320520
18.
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease.
Mar Drugs
; 19(4)2021 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33801706
19.
Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation.
Int J Mol Sci
; 21(20)2020 Oct 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33066042
20.
ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Brain Behav Immun
; 80: 129-145, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30851378