Detalhe da pesquisa
1.
Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator.
J Chem Inf Model
; 64(8): 3477-3487, 2024 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38605537
2.
Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.
Proc Natl Acad Sci U S A
; 117(2): 1049-1058, 2020 01 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31896582
3.
Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder.
Proc Natl Acad Sci U S A
; 116(35): 17290-17297, 2019 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31399543
4.
The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile.
Int J Mol Sci
; 22(6)2021 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33805767
5.
Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS).
Molecules
; 26(2)2021 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33450915
6.
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitors.
Bioorg Med Chem Lett
; 28(10): 1949-1953, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29705141
7.
Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res
; 44(21): 10248-10258, 2016 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27580719
8.
The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP.
Biochemistry
; 56(17): 2328-2337, 2017 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28409622
9.
Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res
; 43(19): 9541-52, 2015 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26358812
10.
An asymmetry that leads to activity.
Proc Natl Acad Sci U S A
; 116(36): 17614-17615, 2019 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31427532
11.
Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II.
PLoS Pathog
; 9(11): e1003732, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24244161
12.
Structure of the S100A4/myosin-IIA complex.
BMC Struct Biol
; 13: 31, 2013 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24252706
13.
Phenothiazines inhibit S100A4 function by inducing protein oligomerization.
Proc Natl Acad Sci U S A
; 107(19): 8605-10, 2010 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-20421509
14.
1H, 13C, and 15N assignments of the mRNA binding protein hnRNP A18.
Biomol NMR Assign
; 17(1): 37-41, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36539586
15.
Characterizing inhibitors of human AP endonuclease 1.
PLoS One
; 18(1): e0280526, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36652434
16.
Membrane binding and pore formation is Ca 2+ -dependent for the Clostridioides difficile binary toxin.
bioRxiv
; 2023 Sep 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37645845
17.
Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery.
J Mol Biol
; 434(23): 167872, 2022 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36354074
18.
1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876).
Biomol NMR Assign
; 15(1): 35-39, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33034833
19.
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1ß/I2PP2A oncoprotein (residues 23-225).
Biomol NMR Assign
; 15(2): 383-387, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34156643
20.
Physiologically Relevant Free Ca2+ Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6.
J Mol Biol
; 433(22): 167272, 2021 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34592217