Detalhe da pesquisa
1.
High-affinity fluorescent ligands for the 5-HT(3) receptor.
Bioorg Med Chem Lett
; 22(2): 1151-5, 2012 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22189135
2.
Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability.
Acta Pharm Sin B
; 11(3): 810-822, 2021 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-33777683
3.
Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74.
Viruses
; 13(3)2021 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33804121
4.
Novel HIV-1 capsid-targeting small molecules of the PF74 binding site.
Eur J Med Chem
; 204: 112626, 2020 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32814250
5.
Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules.
Viruses
; 12(4)2020 04 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32316297
6.
Chemical profiling of HIV-1 capsid-targeting antiviral PF74.
Eur J Med Chem
; 200: 112427, 2020 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32438252
7.
Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-cross-linking Antagonists.
ACS Chem Neurosci
; 10(1): 438-450, 2019 01 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30149702
8.
Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
Eur J Med Chem
; 133: 85-96, 2017 Jun 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28384548
9.
Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity.
J Med Chem
; 60(12): 5045-5056, 2017 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28525279
10.
5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus.
J Med Chem
; 58(9): 4016-28, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25909386
11.
Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.
J Med Chem
; 58(2): 651-64, 2015 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25522204
12.
Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus.
J Med Chem
; 56(21): 8765-80, 2013 Nov 14.
Artigo
Inglês
| MEDLINE | ID: mdl-24102161
13.
5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I.
J Med Chem
; 55(20): 8671-84, 2012 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-23006064
14.
Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives.
J Med Chem
; 53(5): 2324-8, 2010 Mar 11.
Artigo
Inglês
| MEDLINE | ID: mdl-20146481