Detalhe da pesquisa
1.
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys.
Cell
; 185(25): 4811-4825.e17, 2022 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36423629
2.
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
Proc Natl Acad Sci U S A
; 121(14): e2321336121, 2024 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38530888
3.
Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas.
PLoS Comput Biol
; 20(2): e1011847, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38335224
4.
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J Am Chem Soc
; 145(2): 851-863, 2023 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36603206
5.
A Rabbit Model to Study Antibiotic Penetration at the Site of Infection for Nontuberculous Mycobacterial Lung Disease: Macrolide Case Study.
Antimicrob Agents Chemother
; 66(3): e0221221, 2022 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35099272
6.
Sputum lipoarabinomannan (LAM) as a biomarker to determine sputum mycobacterial load: exploratory and model-based analyses of integrated data from four cohorts.
BMC Infect Dis
; 22(1): 327, 2022 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35366820
7.
Lesion Penetration and Activity Limit the Utility of Second-Line Injectable Agents in Pulmonary Tuberculosis.
Antimicrob Agents Chemother
; 65(10): e0050621, 2021 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34252307
8.
Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.
N Engl J Med
; 377(11): 1043-1054, 2017 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28902596
9.
Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific.
PLoS Pathog
; 14(8): e1007223, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30161232
10.
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.
Nature
; 511(7507): 99-103, 2014 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24990750
11.
Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization.
PLoS Med
; 16(4): e1002773, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30939136
12.
Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31383669
13.
Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort study.
Cytokine
; 123: 154759, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31226436
14.
Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29203492
15.
Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery.
Proc Natl Acad Sci U S A
; 112(6): 1827-32, 2015 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25624495
16.
Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.
J Clin Microbiol
; 55(1): 183-198, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27807153
17.
Multidrug-Resistant Tuberculosis Treatment Outcomes in Relation to Treatment and Initial Versus Acquired Second-Line Drug Resistance.
Clin Infect Dis
; 62(4): 418-430, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26508515
18.
Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues.
Anal Chem
; 88(4): 2392-8, 2016 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26814665
19.
Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.
Cell Microbiol
; 17(8): 1085-97, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25653138
20.
Additional drug resistance of multidrug-resistant tuberculosis in patients in 9 countries.
Emerg Infect Dis
; 21(6): 977-83, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25988299