Detalhe da pesquisa
1.
Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay.
Biochemistry
; 60(41): 3114-3124, 2021 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34608799
2.
Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.
BMC Biol
; 14: 5, 2016 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-26787475
3.
Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.
Mol Cell Biol
; 25(17): 7569-79, 2005 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16107704
4.
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.
Mol Biol Cell
; 16(12): 5621-9, 2005 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-16195352
5.
Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.
Cell Chem Biol
; 25(5): 611-618.e3, 2018 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29503208
6.
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.
Mol Cancer Ther
; 16(6): 1010-1020, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28341788
7.
p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2.
Mol Cancer Res
; 3(11): 627-34, 2005 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-16317088
8.
Activation of RAS family members confers resistance to ROS1 targeting drugs.
Oncotarget
; 6(7): 5182-94, 2015 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25691052
9.
Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell
; 27(4): 516-32, 2015 Apr 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25873174
10.
Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment.
Clin Cancer Res
; 21(14): 3327-39, 2015 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25805801
11.
Involvement of GSK-3beta in TWEAK-mediated NF-kappaB activation.
FEBS Lett
; 566(1-3): 60-4, 2004 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-15147869
12.
Cellular interacting proteins of functional screen-derived antiproliferative and cytotoxic peptides discovered using shotgun peptide sequencing.
Chem Biol
; 10(10): 927-37, 2003 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-14583259
13.
Cellular localization and antiproliferative effect of peptides discovered from a functional screen of a retrovirally delivered random peptide library.
Chem Biol
; 10(10): 975-87, 2003 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-14583264
14.
The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function.
EMBO Rep
; 4(10): 953-8, 2003 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12973299