Pesquisa | Secretaria de Estado da Saúde

1.

HSP90 Shapes the Consequences of Human Genetic Variation.

Karras, Georgios I; Yi, Song; Sahni, Nidhi; Fischer, Máté; Xie, Jenny; Vidal, Marc; D'Andrea, Alan D; Whitesell, Luke; Lindquist, Susan.

Cell ; 168(5): 856-866.e12, 2017 Feb 23.

Artigo Inglês | MEDLINE | ID: mdl-28215707

2.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Yang, Xinping; Coulombe-Huntington, Jasmin; Kang, Shuli; Sheynkman, Gloria M; Hao, Tong; Richardson, Aaron; Sun, Song; Yang, Fan; Shen, Yun A; Murray, Ryan R; Spirohn, Kerstin; Begg, Bridget E; Duran-Frigola, Miquel; MacWilliams, Andrew; Pevzner, Samuel J; Zhong, Quan; Wanamaker, Shelly A; Tam, Stanley; Ghamsari, Lila; Sahni, Nidhi; Yi, Song; Rodriguez, Maria D; Balcha, Dawit; Tan, Guihong; Costanzo, Michael; Andrews, Brenda; Boone, Charles; Zhou, Xianghong J; Salehi-Ashtiani, Kourosh; Charloteaux, Benoit; Chen, Alyce A; Calderwood, Michael A; Aloy, Patrick; Roth, Frederick P; Hill, David E; Iakoucheva, Lilia M; Xia, Yu; Vidal, Marc.

Cell ; 164(4): 805-17, 2016 02 11.

Artigo Inglês | MEDLINE | ID: mdl-26871637

3.

Human gene-centered transcription factor networks for enhancers and disease variants.

Fuxman Bass, Juan I; Sahni, Nidhi; Shrestha, Shaleen; Garcia-Gonzalez, Aurian; Mori, Akihiro; Bhat, Numana; Yi, Song; Hill, David E; Vidal, Marc; Walhout, Albertha J M.

Cell ; 161(3): 661-673, 2015 Apr 23.

Artigo Inglês | MEDLINE | ID: mdl-25910213

4.

Widespread macromolecular interaction perturbations in human genetic disorders.

Sahni, Nidhi; Yi, Song; Taipale, Mikko; Fuxman Bass, Juan I; Coulombe-Huntington, Jasmin; Yang, Fan; Peng, Jian; Weile, Jochen; Karras, Georgios I; Wang, Yang; Kovács, István A; Kamburov, Atanas; Krykbaeva, Irina; Lam, Mandy H; Tucker, George; Khurana, Vikram; Sharma, Amitabh; Liu, Yang-Yu; Yachie, Nozomu; Zhong, Quan; Shen, Yun; Palagi, Alexandre; San-Miguel, Adriana; Fan, Changyu; Balcha, Dawit; Dricot, Amelie; Jordan, Daniel M; Walsh, Jennifer M; Shah, Akash A; Yang, Xinping; Stoyanova, Ani K; Leighton, Alex; Calderwood, Michael A; Jacob, Yves; Cusick, Michael E; Salehi-Ashtiani, Kourosh; Whitesell, Luke J; Sunyaev, Shamil; Berger, Bonnie; Barabási, Albert-László; Charloteaux, Benoit; Hill, David E; Hao, Tong; Roth, Frederick P; Xia, Yu; Walhout, Albertha J M; Lindquist, Susan; Vidal, Marc.

Cell ; 161(3): 647-660, 2015 Apr 23.

Artigo Inglês | MEDLINE | ID: mdl-25910212

5.

Playing Hide-and-Seek with Yeast.

Vidal, Marc.

Cell ; 166(5): 1069-1073, 2016 Aug 25.

Artigo Inglês | MEDLINE | ID: mdl-27565335

6.

Interactome networks and human disease.

Vidal, Marc; Cusick, Michael E; Barabási, Albert-László.

Cell ; 144(6): 986-98, 2011 Mar 18.

Artigo Inglês | MEDLINE | ID: mdl-21414488

7.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.

Trepte, Philipp; Secker, Christopher; Olivet, Julien; Blavier, Jeremy; Kostova, Simona; Maseko, Sibusiso B; Minia, Igor; Silva Ramos, Eduardo; Cassonnet, Patricia; Golusik, Sabrina; Zenkner, Martina; Beetz, Stephanie; Liebich, Mara J; Scharek, Nadine; Schütz, Anja; Sperling, Marcel; Lisurek, Michael; Wang, Yang; Spirohn, Kerstin; Hao, Tong; Calderwood, Michael A; Hill, David E; Landthaler, Markus; Choi, Soon Gang; Twizere, Jean-Claude; Vidal, Marc; Wanker, Erich E.

Mol Syst Biol ; 20(4): 428-457, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38467836

8.

New Views of Old Proteins: Clarifying the Enigmatic Proteome.

Burnum-Johnson, Kristin E; Conrads, Thomas P; Drake, Richard R; Herr, Amy E; Iyengar, Ravi; Kelly, Ryan T; Lundberg, Emma; MacCoss, Michael J; Naba, Alexandra; Nolan, Garry P; Pevzner, Pavel A; Rodland, Karin D; Sechi, Salvatore; Slavov, Nikolai; Spraggins, Jeffrey M; Van Eyk, Jennifer E; Vidal, Marc; Vogel, Christine; Walt, David R; Kelleher, Neil L.

Mol Cell Proteomics ; 21(7): 100254, 2022 07.

Artigo Inglês | MEDLINE | ID: mdl-35654359

9.

Cholinergic-related pupil activity reflects level of emotionality during motor performance.

Vidal, Marc; Onderdijk, Kelsey E; Aguilera, Ana M; Six, Joren; Maes, Pieter-Jan; Fritz, Thomas Hans; Leman, Marc.

Eur J Neurosci ; 2023 Apr 28.

Artigo Inglês | MEDLINE | ID: mdl-37118877

10.

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.

Vandermeulen, Charlotte; O'Grady, Tina; Wayet, Jerome; Galvan, Bartimee; Maseko, Sibusiso; Cherkaoui, Majid; Desbuleux, Alice; Coppin, Georges; Olivet, Julien; Ben Ameur, Lamya; Kataoka, Keisuke; Ogawa, Seishi; Hermine, Olivier; Marcais, Ambroise; Thiry, Marc; Mortreux, Franck; Calderwood, Michael A; Van Weyenbergh, Johan; Peloponese, Jean-Marie; Charloteaux, Benoit; Van den Broeke, Anne; Hill, David E; Vidal, Marc; Dequiedt, Franck; Twizere, Jean-Claude.

PLoS Pathog ; 17(9): e1009919, 2021 09.

Artigo Inglês | MEDLINE | ID: mdl-34543356

11.

A mitochondrial protein compendium elucidates complex I disease biology.

Pagliarini, David J; Calvo, Sarah E; Chang, Betty; Sheth, Sunil A; Vafai, Scott B; Ong, Shao-En; Walford, Geoffrey A; Sugiana, Canny; Boneh, Avihu; Chen, William K; Hill, David E; Vidal, Marc; Evans, James G; Thorburn, David R; Carr, Steven A; Mootha, Vamsi K.

Cell ; 134(1): 112-23, 2008 Jul 11.

Artigo Inglês | MEDLINE | ID: mdl-18614015

12.

A protein domain-based interactome network for C. elegans early embryogenesis.

Boxem, Mike; Maliga, Zoltan; Klitgord, Niels; Li, Na; Lemmens, Irma; Mana, Miyeko; de Lichtervelde, Lorenzo; Mul, Joram D; van de Peut, Diederik; Devos, Maxime; Simonis, Nicolas; Yildirim, Muhammed A; Cokol, Murat; Kao, Huey-Ling; de Smet, Anne-Sophie; Wang, Haidong; Schlaitz, Anne-Lore; Hao, Tong; Milstein, Stuart; Fan, Changyu; Tipsword, Mike; Drew, Kevin; Galli, Matilde; Rhrissorrakrai, Kahn; Drechsel, David; Koller, Daphne; Roth, Frederick P; Iakoucheva, Lilia M; Dunker, A Keith; Bonneau, Richard; Gunsalus, Kristin C; Hill, David E; Piano, Fabio; Tavernier, Jan; van den Heuvel, Sander; Hyman, Anthony A; Vidal, Marc.

Cell ; 134(3): 534-45, 2008 Aug 08.

Artigo Inglês | MEDLINE | ID: mdl-18692475

13.

A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice.

Wierbowski, Shayne D; Vo, Tommy V; Falter-Braun, Pascal; Jobe, Timothy O; Kruse, Lars H; Wei, Xiaomu; Liang, Jin; Meyer, Michael J; Akturk, Nurten; Rivera-Erick, Christen A; Cordero, Nicolas A; Paramo, Mauricio I; Shayhidin, Elnur E; Bertolotti, Marta; Tippens, Nathaniel D; Akther, Kazi; Sharma, Rita; Katayose, Yuichi; Salehi-Ashtiani, Kourosh; Hao, Tong; Ronald, Pamela C; Ecker, Joseph R; Schweitzer, Peter A; Kikuchi, Shoshi; Mizuno, Hiroshi; Hill, David E; Vidal, Marc; Moghe, Gaurav D; McCouch, Susan R; Yu, Haiyuan.

Proc Natl Acad Sci U S A ; 117(21): 11836-11842, 2020 05 26.

Artigo Inglês | MEDLINE | ID: mdl-32398372

14.

Homo cerevisiae-Leveraging Yeast for Investigating Protein-Protein Interactions and Their Role in Human Disease.

Laval, Florent; Coppin, Georges; Twizere, Jean-Claude; Vidal, Marc.

Int J Mol Sci ; 24(11)2023 May 24.

Artigo Inglês | MEDLINE | ID: mdl-37298131

15.

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

Hill, Sarah J; Rolland, Thomas; Adelmant, Guillaume; Xia, Xianfang; Owen, Matthew S; Dricot, Amélie; Zack, Travis I; Sahni, Nidhi; Jacob, Yves; Hao, Tong; McKinney, Kristine M; Clark, Allison P; Reyon, Deepak; Tsai, Shengdar Q; Joung, J Keith; Beroukhim, Rameen; Marto, Jarrod A; Vidal, Marc; Gaudet, Suzanne; Hill, David E; Livingston, David M.

Genes Dev ; 28(17): 1957-75, 2014 Sep 01.

Artigo Inglês | MEDLINE | ID: mdl-25184681

16.

Proteome-Scale Human Interactomics.

Luck, Katja; Sheynkman, Gloria M; Zhang, Ivy; Vidal, Marc.

Trends Biochem Sci ; 42(5): 342-354, 2017 05.

Artigo Inglês | MEDLINE | ID: mdl-28284537

17.

Interrogation of kinase genetic interactions provides a global view of PAK1-mediated signal transduction pathways.

Kim, Jae-Hong; Seo, Yeojin; Jo, Myungjin; Jeon, Hyejin; Kim, Young-Seop; Kim, Eun-Jung; Seo, Donggun; Lee, Won-Ha; Kim, Sang Ryong; Yachie, Nozomu; Zhong, Quan; Vidal, Marc; Roth, Frederick P; Suk, Kyoungho.

J Biol Chem ; 295(50): 16906-16919, 2020 12 11.

Artigo Inglês | MEDLINE | ID: mdl-33060198

18.

Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.

Yao, Chen; Joehanes, Roby; Johnson, Andrew D; Huan, Tianxiao; Liu, Chunyu; Freedman, Jane E; Munson, Peter J; Hill, David E; Vidal, Marc; Levy, Daniel.

Am J Hum Genet ; 100(4): 571-580, 2017 Apr 06.

Artigo Inglês | MEDLINE | ID: mdl-28285768

19.

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.

Jo, Myungjin; Chung, Ah Young; Yachie, Nozomu; Seo, Minchul; Jeon, Hyejin; Nam, Youngpyo; Seo, Yeojin; Kim, Eunmi; Zhong, Quan; Vidal, Marc; Park, Hae Chul; Roth, Frederick P; Suk, Kyoungho.

Genome Res ; 27(9): 1487-1500, 2017 09.

Artigo Inglês | MEDLINE | ID: mdl-28596290

20.

How many human proteoforms are there?

Aebersold, Ruedi; Agar, Jeffrey N; Amster, I Jonathan; Baker, Mark S; Bertozzi, Carolyn R; Boja, Emily S; Costello, Catherine E; Cravatt, Benjamin F; Fenselau, Catherine; Garcia, Benjamin A; Ge, Ying; Gunawardena, Jeremy; Hendrickson, Ronald C; Hergenrother, Paul J; Huber, Christian G; Ivanov, Alexander R; Jensen, Ole N; Jewett, Michael C; Kelleher, Neil L; Kiessling, Laura L; Krogan, Nevan J; Larsen, Martin R; Loo, Joseph A; Ogorzalek Loo, Rachel R; Lundberg, Emma; MacCoss, Michael J; Mallick, Parag; Mootha, Vamsi K; Mrksich, Milan; Muir, Tom W; Patrie, Steven M; Pesavento, James J; Pitteri, Sharon J; Rodriguez, Henry; Saghatelian, Alan; Sandoval, Wendy; Schlüter, Hartmut; Sechi, Salvatore; Slavoff, Sarah A; Smith, Lloyd M; Snyder, Michael P; Thomas, Paul M; Uhlén, Mathias; Van Eyk, Jennifer E; Vidal, Marc; Walt, David R; White, Forest M; Williams, Evan R; Wohlschlager, Therese; Wysocki, Vicki H.

Nat Chem Biol ; 14(3): 206-214, 2018 02 14.

Artigo Inglês | MEDLINE | ID: mdl-29443976

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