Detalhe da pesquisa
1.
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
J Biol Chem
; 295(15): 5081-5094, 2020 04 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32152226
2.
piRNAs as Modulators of Disease Pathogenesis.
Int J Mol Sci
; 22(5)2021 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33673453
3.
Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection.
Int J Mol Sci
; 21(24)2020 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33322418
4.
Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells.
Int J Mol Sci
; 21(14)2020 Jul 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32664627
5.
Filamin A Is Involved in HIV-1 Vpu-mediated Evasion of Host Restriction by Modulating Tetherin Expression.
J Biol Chem
; 291(8): 4236-46, 2016 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-26742839
6.
Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28461309
7.
A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy.
J Biol Chem
; 290(42): 25439-51, 2015 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26330555
8.
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
Antimicrob Agents Chemother
; 60(2): 1058-66, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26643331
9.
VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.
J Infect Dis
; 212(9): 1439-48, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25883390
10.
Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth.
J Lipid Res
; 56(2): 331-41, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25424002
11.
Cocaine enhances HIV-1-induced CD4(+) T-cell apoptosis: implications in disease progression in cocaine-abusing HIV-1 patients.
Am J Pathol
; 184(4): 927-936, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24486327
12.
VNI cures acute and chronic experimental Chagas disease.
J Infect Dis
; 208(3): 504-11, 2013 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23372180
13.
Cellular response to Trypanosoma cruzi infection induces secretion of defensin α-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection.
Infect Immun
; 81(11): 4139-48, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23980110
14.
Defective HIV-1 particle assembly in AP-3-deficient cells derived from patients with Hermansky-Pudlak syndrome type 2.
J Virol
; 86(20): 11242-53, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22875976
15.
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms.
Biochem J
; 443(1): 267-77, 2012 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22176028
16.
Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells.
PLoS Negl Trop Dis
; 16(1): e0010074, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34986160
17.
Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts.
Immune Netw
; 22(6): e51, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36627941
18.
Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi.
J Biol Chem
; 285(33): 25582-90, 2010 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-20530488
19.
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
J Biol Chem
; 285(3): 1773-80, 2010 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19923211
20.
Respiratory and Neurological Disease across Different Ethnic Groups Is Influenced by the Microbiome.
Microorganisms
; 9(9)2021 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34576860