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1.
Ned Tijdschr Geneeskd ; 152(18): 1052-6, 2008 May 03.
Artigo em Holandês | MEDLINE | ID: mdl-18547028

RESUMO

A palpable abnormality of the breast was found in three women, one aged 57 and two aged 41. The first two patients predominantly showed the characteristics of a purulent inflammation, and on mammogram the third patient appeared to have mastitis carcinomatosa. Histopathological investigation revealed a lobular, non-caseating granulomatous inflammation. They were treated with prednisone and the first and third patients also received azathioprine. After some time, the condition recurred in the contralateral breast in the second and third patients. Once again, medicinal treatment was given. When a palpable tumour of the breast is found the primary goal is to exclude malignancy. Granulomatous lobular mastitis is a rare and benign tumour of the breast that clinically mimics carcinoma. Often, conventional imaging does not lead to the diagnosis. A histological needle biopsy is the best way to reach a diagnosis. Immunosuppressive therapy is effective and is preferred over surgery.


Assuntos
Granuloma/diagnóstico , Granuloma/tratamento farmacológico , Mastite/diagnóstico , Mastite/tratamento farmacológico , Adulto , Anti-Inflamatórios/uso terapêutico , Azatioprina/uso terapêutico , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/patologia , Citodiagnóstico , Diagnóstico Diferencial , Feminino , Granuloma/patologia , Humanos , Mastite/patologia , Pessoa de Meia-Idade , Prednisona/uso terapêutico , Recidiva , Resultado do Tratamento
2.
Ned Tijdschr Geneeskd ; 150(27): 1503-7, 2006 Jul 08.
Artigo em Holandês | MEDLINE | ID: mdl-16892612

RESUMO

Care for the polytraumatized patient in the pre-hospital phase has improved rapidly in recent years. This has resulted in more patients being alive on arrival at the hospital. The treatment of polytraumatized patients requires a different approach to that of regular trauma patients because they are threatened not only by the injuries themselves but also by the metabolic disruptions that follow. Therefore, the concept of damage control surgery (DCS) has been developed with the primary aim of controlling the life-threatening situation without immediate definitive repair of the sustained injuries. DCS describes a triphasic approach for abdominal and thoracic injuries and for injuries of the pelvic and extremities. The first phase aims at surgical intervention to stop the bleeding and to prevent further contamination. The second phase consists of resuscitation on the Intensive Care Unit and the third phase aims at definitive repair of the sustained injuries. Despite the low level of evidence found in the literature, DCS seems to reduce mortality rates in polytraumatized patients. Therefore, when initiated correctly and at the right moment, it appears to be a promising technique.


Assuntos
Cuidados Críticos/métodos , Tratamento de Emergência/métodos , Traumatismo Múltiplo/cirurgia , Traumatismos Abdominais/mortalidade , Traumatismos Abdominais/cirurgia , Cuidados Críticos/normas , Tratamento de Emergência/normas , Humanos , Traumatismo Múltiplo/mortalidade , Países Baixos , Reoperação , Ressuscitação , Taxa de Sobrevida
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