Detalhe da pesquisa
1.
Development and verification of a full physiologically-based pharmacokinetic model for sublingual buprenorphine in healthy adult volunteers that accounts for nonlinear bioavailability.
Drug Metab Dispos
; 2024 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38769016
2.
Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis.
Clin Gastroenterol Hepatol
; 21(5): 1338-1347, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36031093
3.
Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury.
J Antimicrob Chemother
; 78(2): 478-487, 2023 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36545869
4.
Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy.
J Antimicrob Chemother
; 78(9): 2140-2147, 2023 09 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37466170
5.
Artificial Intelligence and Machine Learning Approaches to Facilitate Therapeutic Drug Management and Model-Informed Precision Dosing.
Ther Drug Monit
; 45(2): 143-150, 2023 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36750470
6.
Model-Informed Estimation of Acutely Decreased Tacrolimus Clearance and Subsequent Dose Individualization in a Pediatric Renal Transplant Patient With Posterior Reversible Encephalopathy Syndrome.
Ther Drug Monit
; 45(3): 376-382, 2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36728342
7.
Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy.
Ther Drug Monit
; 45(6): 832-836, 2023 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37725684
8.
Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment.
Antimicrob Agents Chemother
; 66(1): e0142721, 2022 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34633847
9.
A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures.
Ann Neurol
; 89(2): 327-340, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33201535
10.
Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care.
Br J Clin Pharmacol
; 88(4): 1418-1426, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32529759
11.
Model-informed precision dosing for alemtuzumab in paediatric and young adult patients undergoing allogeneic haematopoietic cell transplantation.
Br J Clin Pharmacol
; 88(1): 248-259, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34182590
12.
Test-dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non-malignant disorders.
Br J Clin Pharmacol
; 88(1): 115-127, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34075614
13.
Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines.
Cardiovasc Drugs Ther
; 36(4): 589-604, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33689087
14.
Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics-guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia.
Br J Haematol
; 194(3): 617-625, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34227124
15.
Pharmacokinetic modelling to predict risk of ototoxicity with intravenous tobramycin treatment in cystic fibrosis.
J Antimicrob Chemother
; 76(11): 2923-2931, 2021 10 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34379758
16.
Hydroyxurea improves cerebral oxygen saturation in children with sickle cell anemia.
Am J Hematol
; 96(5): 538-544, 2021 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33534136
17.
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.
Ther Drug Monit
; 43(2): 150-200, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33711005
18.
A POETIC Phase II study of continuous oral everolimus in recurrent, radiographically progressive pediatric low-grade glioma.
Pediatr Blood Cancer
; 68(2): e28787, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33140540
19.
Hydroxyurea Exposure in Lactation: a Pharmacokinetics Study (HELPS).
J Pediatr
; 222: 236-239, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32171562
20.
Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients.
Br J Clin Pharmacol
; 86(5): 933-943, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31851762