RESUMO
Weak radiative decays of the B mesons belong to the most important flavor changing processes that provide constraints on physics at the TeV scale. In the derivation of such constraints, accurate standard model predictions for the inclusive branching ratios play a crucial role. In the current Letter we present an update of these predictions, incorporating all our results for the O(α_{s}^{2}) and lower-order perturbative corrections that have been calculated after 2006. New estimates of nonperturbative effects are taken into account, too. For the CP- and isospin-averaged branching ratios, we find B_{sγ}=(3.36±0.23)×10^{-4} and B_{dγ}=(1.73_{-0.22}^{+0.12})×10^{-5}, for E_{γ}>1.6 GeV. Both results remain in agreement with the current experimental averages. Normalizing their sum to the inclusive semileptonic branching ratio, we obtain R_{γ}≡(B_{sγ}+B_{dγ})/B_{câν}=(3.31±0.22)×10^{-3}. A new bound from B_{sγ} on the charged Higgs boson mass in the two-Higgs-doublet-model II reads M_{H^{±}}>480 GeV at 95% C.L.
RESUMO
To evaluate the efficacy and safety of conversion from cyclosporine to tacrolimus, we analyzed 55 kidney transplant patients who were converted due to cosmetic reasons in 42 patients, acute rejection in 2 patients, and other causes in 11 patients. At the doses and levels used, the development of diabetes mellitus was minimized. Disappearance of cosmetic side-effects and improvement of cardiovascular risk factors, together with conservation of renal function, encourage us to use tacrolimus as an efficacious and safe immunosuppressive therapy.
Assuntos
Ciclosporina/efeitos adversos , Transplante de Rim/imunologia , Tacrolimo/uso terapêutico , Adulto , Glicemia/metabolismo , Pressão Sanguínea , Colesterol/sangue , Feminino , Seguimentos , Humanos , Imunossupressores/efeitos adversos , Imunossupressores/uso terapêutico , Masculino , Estudos Retrospectivos , Segurança , Fatores de Tempo , Ácido Úrico/sangueRESUMO
Analysis of one case of benign vesical primitive connective tumour, with pathoanatomical description of vesical fibroma. The interest of this case rests on its rarity and uncertain origin, still subject to controversy. The paper presents the tumour's clinical history, pathological anatomy, therapeutical approach and prognosis.
Assuntos
Fibroma/diagnóstico , Neoplasias da Bexiga Urinária/diagnóstico , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
Intussusception is a rare form of intestinal obstruction in adults. Most cases are caused by malignant lesions in the intestinal wall, which in exceptional cases are caused by metastases. The initial manifestation of lung cancer as metastasis to the gastrointestinal tract is an extremely rare event. In most cases metastases are diagnosed after the primary lung tumour, when potentially life-threatening complications such as perforation, obstruction or haemorrhage develop, often requiring emergency surgery. Regardless of treatment, these patients have very poor prognosis due to the advanced stage of their disease. The study describes the case of a 48-year-old man presenting at the emergency department with a bowel obstruction of a week's duration, who was diagnosed via CT scan with small-bowel intussusception, and via chest x-ray with a suspicious lung nodule. Emergency surgery was performed, with intestinal resection of the invaginated area and anastomosis. Postoperative recovery was uneventful. The histopathological diagnosis was intestinal metastasis from lung carcinoma. Stage IV primary malignant lung tumour was confirmed, with spread through the lungs, bones, brain and metastases in both adrenal glands. Received palliative treatment with radiation and chemotherapy, and died five months after diagnosis.
Assuntos
Carcinoma/complicações , Carcinoma/secundário , Doenças do Íleo/etiologia , Neoplasias do Íleo/complicações , Neoplasias do Íleo/secundário , Intussuscepção/etiologia , Neoplasias Pulmonares/complicações , Neoplasias Pulmonares/patologia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
La invaginación intestinal es una causa muy poco frecuente de obstrucción intestinal en el adulto. La mayoría están causadas por lesiones malignas en la pared intestinal, siendo excepcional que se produzcan por metástasis. La manifestación inicial del cáncer de pulmón como metástasis en el tracto gastrointestinal es un hecho extremadamente raro. En la mayoría de los casos las metástasis se diagnostican después del tumor primario pulmonar, cuando desarrollan complicaciones potencialmente mortales como perforación, obstrucción o hemorragia, que a menudo requieren una intervención quirúrgica urgente. Independientemente del tratamiento, estos pacientes tienen un pronóstico muy sombrío dado el estado avanzado de su enfermedad. Describimos el caso un hombre de 48 años con un cuadro de obstrucción intestinal de una semana de evolución, que fue diagnosticado en el servicio de Urgencias mediante tomografía computarizada de invaginación de intestino delgado, y en radiografía simple de tórax de nódulo pulmonar sospechoso. Se decidió intervención quirúrgica urgente, realizándose resección intestinal de la zona invaginada y anastomosis, presentando un postoperatorio sin incidencias. El diagnóstico anatomopatológico fue de metástasis intestinal de carcinoma de pulmón. Se confirmó el tumor maligno primario de pulmón en estadio IV, con diseminación pulmonar, ósea, cerebral y metástasis en ambas glándulas suprarrenales. Recibió tratamiento paliativo con radioterapia y quimioterapia, falleciendo transcurridos 5 meses del diagnóstico (AU)
Intussusception is a rare form of intestinal obstruction in adults. Most cases are caused by malignant lesions in the intestinal wall, which in exceptional cases are caused by metastases. The initial manifestation of lung cancer as metastasis to the gastrointestinal tract is an extremely rare event. In most cases metastases are diagnosed after the primary lung tumour, when potentially life-threatening complications such as perforation, obstruction or haemorrhage develop, often requiring emergency surgery. Regardless of treatment, these patients have very poor prognosis due to the advanced stage of their disease. The study describes the case of a 48-year-old man presenting at the emergency department with a bowel obstruction of a week's duration, who was diagnosed via CT scan with small-bowel intussusception, and via chest x-ray with a suspicious lung nodule. Emergency surgery was performed, with intestinal resection of the invaginated area and anastomosis. Postoperative recovery was uneventful. The histopathological diagnosis was intestinal metastasis from lung carcinoma. Stage IV primary malignant lung tumour was confirmed, with spread through the lungs, bones, brain and metastases in both adrenal glands. Received palliative treatment with radiation and chemotherapy, and died five months after diagnosis (AU)
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Intussuscepção/complicações , Intussuscepção/diagnóstico , Intussuscepção/patologia , Neoplasias Pulmonares/complicações , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/cirurgia , Intussuscepção/fisiopatologia , Intussuscepção , Neoplasias Primárias Múltiplas/complicaçõesRESUMO
We report on three patients with a functioning solitary kidney that required placement of a double-J catheter. All three patients presented with obstruction of urinary drainage within three weeks. In one patient clots were observed inside the catheter. The catheters of the other two patients, however, showed no signs of obstruction. Two patients presented symptoms and signs of reduced volume of diuresis and the other a deteriorated general condition. In patients with a normally functioning contralateral renal unit, deterioration of renal function of the unit with an indwelling double-J catheter may probably go undetected. A compromised urinary drainage of the renal unit with an indwelling double-J catheter is not necessarily associated with obstruction of the catheter lumen. Urinary drainage around an obstructed double-J catheter is not sufficient in all cases.
Assuntos
Obstrução Ureteral/diagnóstico , Cateterismo Urinário/instrumentação , Adulto , Idoso , Drenagem , Feminino , Humanos , MasculinoRESUMO
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