Pesquisa | Secretaria de Estado da Saúde

1.

Deciphering breast cancer: from biology to the clinic.

Nolan, Emma; Lindeman, Geoffrey J; Visvader, Jane E.

Cell ; 186(8): 1708-1728, 2023 04 13.

Artigo Inglês | MEDLINE | ID: mdl-36931265

2.

Stem Cells and the Differentiation Hierarchy in Mammary Gland Development.

Fu, Nai Yang; Nolan, Emma; Lindeman, Geoffrey J; Visvader, Jane E.

Physiol Rev ; 100(2): 489-523, 2020 04 01.

Artigo Inglês | MEDLINE | ID: mdl-31539305

3.

A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast.

Pal, Bhupinder; Chen, Yunshun; Vaillant, François; Capaldo, Bianca D; Joyce, Rachel; Song, Xiaoyu; Bryant, Vanessa L; Penington, Jocelyn S; Di Stefano, Leon; Tubau Ribera, Nina; Wilcox, Stephen; Mann, Gregory B; Papenfuss, Anthony T; Lindeman, Geoffrey J; Smyth, Gordon K; Visvader, Jane E.

EMBO J ; 40(11): e107333, 2021 06 01.

Artigo Inglês | MEDLINE | ID: mdl-33950524

4.

Towards resolution of the intron retention paradox in breast cancer.

Shah, Jaynish S; Milevskiy, Michael J G; Petrova, Veronika; Au, Amy Y M; Wong, Justin J L; Visvader, Jane E; Schmitz, Ulf; Rasko, John E J.

Breast Cancer Res ; 24(1): 100, 2022 12 29.

Artigo Inglês | MEDLINE | ID: mdl-36581993

5.

Lgr5⁺ pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis.

Ang, Chow Hiang; Hsu, Shih Han; Guo, Fusheng; Tan, Chong Teik; Yu, Victor C; Visvader, Jane E; Chow, Pierce K H; Fu, Nai Yang.

Proc Natl Acad Sci U S A ; 116(39): 19530-19540, 2019 09 24.

Artigo Inglês | MEDLINE | ID: mdl-31488716

6.

Mammary stem cells and the differentiation hierarchy: current status and perspectives.

Visvader, Jane E; Stingl, John.

Genes Dev ; 28(11): 1143-58, 2014 Jun 01.

Artigo Inglês | MEDLINE | ID: mdl-24888586

7.

The Cellular Organization of the Mammary Gland: Insights From Microscopy.

Dawson, Caleb A; Visvader, Jane E.

J Mammary Gland Biol Neoplasia ; 26(1): 71-85, 2021 03.

Artigo Inglês | MEDLINE | ID: mdl-33835387

8.

Single cell transcriptome atlas of mouse mammary epithelial cells across development.

Pal, Bhupinder; Chen, Yunshun; Milevskiy, Michael J G; Vaillant, François; Prokopuk, Lexie; Dawson, Caleb A; Capaldo, Bianca D; Song, Xiaoyu; Jackling, Felicity; Timpson, Paul; Lindeman, Geoffrey J; Smyth, Gordon K; Visvader, Jane E.

Breast Cancer Res ; 23(1): 69, 2021 06 29.

Artigo Inglês | MEDLINE | ID: mdl-34187545

9.

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids.

Michalak, Ewa M; Milevskiy, Michael J G; Joyce, Rachel M; Dekkers, Johanna F; Jamieson, Paul R; Pal, Bhupinder; Dawson, Caleb A; Hu, Yifang; Orkin, Stuart H; Alexander, Warren S; Lindeman, Geoffrey J; Smyth, Gordon K; Visvader, Jane E.

PLoS Biol ; 16(8): e2004986, 2018 08.

Artigo Inglês | MEDLINE | ID: mdl-30080881

10.

Derivation of a robust mouse mammary organoid system for studying tissue dynamics.

Jamieson, Paul R; Dekkers, Johanna F; Rios, Anne C; Fu, Nai Yang; Lindeman, Geoffrey J; Visvader, Jane E.

Development ; 144(6): 1065-1071, 2017 03 15.

Artigo Inglês | MEDLINE | ID: mdl-27993977

11.

In situ identification of bipotent stem cells in the mammary gland.

Rios, Anne C; Fu, Nai Yang; Lindeman, Geoffrey J; Visvader, Jane E.

Nature ; 506(7488): 322-7, 2014 Feb 20.

Artigo Inglês | MEDLINE | ID: mdl-24463516

12.

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.

Jain, Reema; Sheridan, Julie M; Policheni, Antonia; Heinlein, Melanie; Gandolfo, Luke C; Dewson, Grant; Smyth, Gordon K; Sansom, Stephen N; Fu, Nai Yang; Visvader, Jane E; Holländer, Georg A; Strasser, Andreas; Gray, Daniel H D.

Blood ; 130(23): 2504-2515, 2017 12 07.

Artigo Inglês | MEDLINE | ID: mdl-28972012

13.

Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression.

Grassmeyer, Justin; Mukherjee, Malini; deRiso, Jennifer; Hettinger, Casey; Bailey, Monica; Sinha, Satrajit; Visvader, Jane E; Zhao, Haotian; Fogarty, Eric; Surendran, Kameswaran.

Dev Biol ; 424(1): 77-89, 2017 04 01.

Artigo Inglês | MEDLINE | ID: mdl-28215940

14.

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.

O'Brien, Carmel M; Chy, Hun S; Zhou, Qi; Blumenfeld, Shiri; Lambshead, Jack W; Liu, Xiaodong; Kie, Joshua; Capaldo, Bianca D; Chung, Tung-Liang; Adams, Timothy E; Phan, Tram; Bentley, John D; McKinstry, William J; Oliva, Karen; McMurrick, Paul J; Wang, Yu-Chieh; Rossello, Fernando J; Lindeman, Geoffrey J; Chen, Di; Jarde, Thierry; Clark, Amander T; Abud, Helen E; Visvader, Jane E; Nefzger, Christian M; Polo, Jose M; Loring, Jeanne F; Laslett, Andrew L.

Stem Cells ; 35(3): 626-640, 2017 03.

Artigo Inglês | MEDLINE | ID: mdl-28009074

15.

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

Dobrolecki, Lacey E; Airhart, Susie D; Alferez, Denis G; Aparicio, Samuel; Behbod, Fariba; Bentires-Alj, Mohamed; Brisken, Cathrin; Bult, Carol J; Cai, Shirong; Clarke, Robert B; Dowst, Heidi; Ellis, Matthew J; Gonzalez-Suarez, Eva; Iggo, Richard D; Kabos, Peter; Li, Shunqiang; Lindeman, Geoffrey J; Marangoni, Elisabetta; McCoy, Aaron; Meric-Bernstam, Funda; Piwnica-Worms, Helen; Poupon, Marie-France; Reis-Filho, Jorge; Sartorius, Carol A; Scabia, Valentina; Sflomos, George; Tu, Yizheng; Vaillant, François; Visvader, Jane E; Welm, Alana; Wicha, Max S; Lewis, Michael T.

Cancer Metastasis Rev ; 35(4): 547-573, 2016 12.

Artigo Inglês | MEDLINE | ID: mdl-28025748

16.

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.

Best, Sarah A; Hutt, Karla J; Fu, Nai Yang; Vaillant, François; Liew, Seng H; Hartley, Lynne; Scott, Clare L; Lindeman, Geoffrey J; Visvader, Jane E.

Development ; 141(16): 3159-64, 2014 Aug.

Artigo Inglês | MEDLINE | ID: mdl-25038044

17.

Cells of origin in cancer.

Visvader, Jane E.

Nature ; 469(7330): 314-22, 2011 Jan 20.

Artigo Inglês | MEDLINE | ID: mdl-21248838

18.

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland.

Godde, Nathan J; Sheridan, Julie M; Smith, Lorey K; Pearson, Helen B; Britt, Kara L; Galea, Ryan C; Yates, Laura L; Visvader, Jane E; Humbert, Patrick O.

PLoS Genet ; 10(5): e1004323, 2014 May.

Artigo Inglês | MEDLINE | ID: mdl-24852022

19.

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.

Visvader, Jane E.

Genes Dev ; 23(22): 2563-77, 2009 Nov 15.

Artigo Inglês | MEDLINE | ID: mdl-19933147

20.

Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4.

Baron, Kyla D; Al-Zahrani, Khalid; Conway, Jillian; Labrèche, Cédrik; Storbeck, Christopher J; Visvader, Jane E; Sabourin, Luc A.

Biochim Biophys Acta ; 1853(7): 1683-92, 2015 Jul.

Artigo Inglês | MEDLINE | ID: mdl-25882817

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