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US Army Med Dep J ; : 27-32, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25074599

RESUMO

The Anigen Rapid Rabies Antigen Test Kit (Bionote, Inc, Hwaseong, Korea) was evaluated using 80 clinical samples collected by US military veterinary units. Samples for the study were obtained from brain specimens of domestic and wildlife animals that were submitted to the US Army Public Health Command's Veterinary Laboratory Europe in Landstuhl, Germany, for rabies testing with the direct fluorescent antibody test. The rapid immunodiagnostic test was able to detect rabies virus antigen in clinical samples of brain tissue. The rapid immunodiagnostic test had an overall sensitivity of 96.9% and specificity of 100% when compared to the direct fluorescent antibody test. The rapid immunodiagnostic test for rabies virus antigen detection is a straightforward test that can be run under field conditions and without a microscope or electricity, and yield results in 5 to 10 minutes. This rapid immunodiagnostic test is a quick, inexpensive, and easy to use surveillance tool that can identify rabies positive animals and help focus targeted control measures with the goal of reducing the rabies burden.


Assuntos
Antígenos Virais/isolamento & purificação , Testes Imunológicos/métodos , Medicina Militar , Vírus da Raiva/isolamento & purificação , Raiva/diagnóstico , África , Encéfalo/virologia , Europa (Continente) , Técnica Direta de Fluorescência para Anticorpo , Humanos , Oriente Médio , Vigilância da População , Vírus da Raiva/imunologia , Sensibilidade e Especificidade , Serviço Veterinário Militar
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