Detalhe da pesquisa
1.
Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement.
Haematologica
; 108(3): 717-731, 2023 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35484682
2.
Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia.
Haematologica
; 106(4): 1056-1066, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32139432
3.
Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.
Haematologica
; 104(9): 1804-1811, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30655370
4.
Allogeneic hematopoietic cell transplantation in Farber disease.
J Inherit Metab Dis
; 42(2): 286-294, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30815900
5.
The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.
Blood
; 127(16): 1998-2006, 2016 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26869395
6.
Accelerating drug development in pediatric cancer: a novel Phase I study design of venetoclax in relapsed/refractory malignancies.
Future Oncol
; 14(21): 2115-2129, 2018 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-29595064
7.
From class waivers to precision medicine in paediatric oncology.
Lancet Oncol
; 18(7): e394-e404, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28677575
8.
A population pharmacokinetic model of AT9283 in adults and children to predict the maximum tolerated dose in children with leukaemia.
Br J Clin Pharmacol
; 83(8): 1713-1722, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28177130
9.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.
Blood
; 124(23): 3420-30, 2014 Nov 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25253770
10.
CD19: A multifunctional immunological target molecule and its implications for Blineage acute lymphoblastic leukemia.
Pediatr Blood Cancer
; 62(7): 1144-8, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25755168
11.
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia.
Genes Chromosomes Cancer
; 51(3): 250-6, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22072526
12.
Novel Adaption of the SARC-F Score to Classify Pediatric Hemato-Oncology Patients with Functional Sarcopenia.
Cancers (Basel)
; 15(1)2023 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36612316
13.
Have we made progress in taking care of adolescents and young adults with cancer? Results of a European multi-professional survey.
Tumori
; 109(6): 546-554, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37486101
14.
The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study.
Haematologica
; 97(1): 21-9, 2012 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21933851
15.
Selumetinib in combination with dexamethasone for the treatment of relapsed/refractory RAS-pathway mutated paediatric and adult acute lymphoblastic leukaemia (SeluDex): study protocol for an international, parallel-group, dose-finding with expansion phase I/II trial.
BMJ Open
; 12(3): e059872, 2022 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35246426
16.
Targeted inhibitors and antibody immunotherapies: Novel therapies for paediatric leukaemia and lymphoma.
Eur J Cancer
; 164: 1-17, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35121370
17.
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia.
Cell Rep Med
; 3(8): 100717, 2022 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35977468
18.
MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
Leukemia
; 35(12): 3394-3405, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34007050
19.
Flow minimal residual disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34+CD38lowCD19+ in B-lineage childhood acute lymphoblastic leukemia.
Haematologica
; 95(4): 679-83, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19951974
20.
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
Cancer Cell
; 34(4): 626-642.e8, 2018 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30300583