Detalhe da pesquisa
1.
TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol
; 204(7): 1943-1953, 2020 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32102902
2.
Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model.
J Virol
; 91(10)2017 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28275182
3.
Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors.
Mol Ther
; 24(11): 1913-1925, 2016 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-27401039
4.
TCR affinity and specificity requirements for human regulatory T-cell function.
Blood
; 119(15): 3420-30, 2012 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22318202
5.
Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies.
Eur J Immunol
; 42(12): 3174-9, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22949370
6.
Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors.
Cancer Immunol Immunother
; 62(4): 773-85, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23263452
7.
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen.
Nat Commun
; 13(1): 5333, 2022 09 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36088370
8.
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.
J Clin Invest
; 130(5): 2673-2688, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32310221
9.
Directed evolution of human T-cell receptors with picomolar affinities by phage display.
Nat Biotechnol
; 23(3): 349-54, 2005 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-15723046
10.
An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules.
PLoS One
; 13(10): e0205491, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30321203
11.
Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor.
Proteins
; 67(1): 65-74, 2007 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17243170
12.
Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.
Protein Eng Des Sel
; 20(8): 397-403, 2007 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-17644531
13.
Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 63(Pt 9): 758-60, 2007 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17768347
14.
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep
; 6: 18851, 2016 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26758806
15.
Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.
Sci Transl Med
; 5(197): 197ra103, 2013 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23926201
16.
Monoclonal TCR-redirected tumor cell killing.
Nat Med
; 18(6): 980-7, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22561687
17.
High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation.
Protein Cell
; 1(12): 1118-27, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21213105
18.
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.
Nat Med
; 14(12): 1390-5, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18997777
19.
Cutting edge: Evidence of direct TCR alpha-chain interaction with superantigen.
J Immunol
; 179(5): 2700-4, 2007 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17709482
20.
Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.
J Biol Chem
; 280(3): 1882-92, 2005 Jan 21.
Artigo
Inglês
| MEDLINE | ID: mdl-15531581