Detalhe da pesquisa
1.
Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production.
J Immunol
; 210(8): 1108-1122, 2023 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36881874
2.
Dual antigen-targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia.
Blood
; 140(23): 2451-2462, 2022 12 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35917442
3.
Engineering of CD34+ progenitor-derived natural killer cells with higher-affinity CD16a for enhanced antibody-dependent cellular cytotoxicity.
Cytotherapy
; 26(3): 252-260, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38127030
4.
Pluripotent stem cell-derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity.
Blood
; 135(6): 399-410, 2020 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31856277
5.
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.
Mol Ther
; 28(1): 52-63, 2020 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31704085
6.
Blocking ADAM17 Function with a Monoclonal Antibody Improves Sepsis Survival in a Murine Model of Polymicrobial Sepsis.
Int J Mol Sci
; 21(18)2020 Sep 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32932701
7.
Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17.
J Biol Chem
; 292(15): 6339-6351, 2017 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28232483
8.
Anti-ADAM17 monoclonal antibody MEDI3622 increases IFNγ production by human NK cells in the presence of antibody-bound tumor cells.
Cancer Immunol Immunother
; 67(9): 1407-1416, 2018 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-29978334
9.
NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).
Blood
; 121(18): 3599-608, 2013 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23487023
10.
ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils.
Biochim Biophys Acta
; 1833(3): 680-5, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23228566
11.
Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers.
Prostate
; 74(10): 1059-67, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24854630
12.
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells.
bioRxiv
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38798522
13.
Detection of Antibody-Dependent Cell-Mediated Cytotoxicity-Supporting Antibodies by NK-92-CD16A Cell Externalization of CD107a: Recognition of Antibody Afucosylation and Assay Optimization.
Antibodies (Basel)
; 12(3)2023 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37489366
14.
iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting.
J Immunother Cancer
; 11(12)2023 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38056893
15.
Different signaling pathways stimulate a disintegrin and metalloprotease-17 (ADAM17) in neutrophils during apoptosis and activation.
J Biol Chem
; 286(45): 38980-8, 2011 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21949123
16.
ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis.
J Immunol
; 184(8): 4447-54, 2010 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20220092
17.
An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model.
Front Immunol
; 13: 918881, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35757773
18.
Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells.
Front Immunol
; 13: 841859, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35281028
19.
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Nat Commun
; 13(1): 7341, 2022 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-36446823
20.
Regulation of mature ADAM17 by redox agents for L-selectin shedding.
J Immunol
; 182(4): 2449-57, 2009 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19201900