Detalhe da pesquisa
1.
The Influence of a Genetic Variant in CCDC78 on LMNA-Associated Skeletal Muscle Disease.
Int J Mol Sci
; 25(9)2024 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38732148
2.
Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling.
Hum Mol Genet
; 28(3): 351-371, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30239736
3.
Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells.
Nat Mater
; 19(4): 464-473, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31844279
4.
In Silico and In Vivo Analysis of Amino Acid Substitutions That Cause Laminopathies.
Int J Mol Sci
; 22(20)2021 Oct 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34681887
5.
Myopathic lamin mutations cause reductive stress and activate the nrf2/keap-1 pathway.
PLoS Genet
; 11(5): e1005231, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25996830
6.
Stimulating conversations between HP1a and histone demethylase dKDM4A.
Mol Cell
; 32(5): 601-2, 2008 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-19061634
7.
Human heterochromatin protein 1α promotes nucleosome associations that drive chromatin condensation.
J Biol Chem
; 289(10): 6850-6861, 2014 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24415761
8.
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling.
Hum Mol Genet
; 22(12): 2335-49, 2013 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23427149
9.
Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.
J Biol Chem
; 288(33): 23858-67, 2013 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-23839987
10.
LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle.
Hum Mol Genet
; 21(7): 1544-56, 2012 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22186027
11.
The role of Drosophila Lamin C in muscle function and gene expression.
Development
; 137(18): 3067-77, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20702563
12.
Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases.
Cells
; 12(8)2023 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37190051
13.
Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope.
Mol Biol Cell
; : mbcE21100527, 2023 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37585285
14.
Shining Light on the Dark Side of the Genome.
Cells
; 11(3)2022 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35159140
15.
Effects of mutant lamins on nucleo-cytoskeletal coupling in Drosophila models of LMNA muscular dystrophy.
Front Cell Dev Biol
; 10: 934586, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36120560
16.
Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins.
Redox Biol
; 48: 102196, 2021 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34872044
17.
Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein.
Genetics
; 180(1): 133-45, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-18723885
18.
Linking Heterochromatin Protein 1 (HP1) to cancer progression.
Mutat Res
; 647(1-2): 13-20, 2008 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18926834
19.
Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan.
Aging Cell
; 17(3): e12747, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29575479
20.
Connections between epigenetic gene silencing and human disease.
Mutat Res
; 618(1-2): 163-74, 2007 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17306846