Detalhe da pesquisa
1.
Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia.
J Neurochem
; 136 Suppl 1: 49-62, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25708596
2.
Loss of endophilin-B1 exacerbates Alzheimer's disease pathology.
Brain
; 138(Pt 7): 2005-19, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25981964
3.
Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons.
J Neurosci
; 34(7): 2674-83, 2014 Feb 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24523556
4.
p53 and mitochondrial function in neurons.
Biochim Biophys Acta
; 1842(8): 1186-97, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24412988
5.
Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death.
J Neurosci
; 33(4): 1357-65, 2013 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-23345212
6.
Selective forelimb impairment in rats expressing a pathological TDP-43 25 kDa C-terminal fragment to mimic amyotrophic lateral sclerosis.
Mol Ther
; 21(7): 1324-34, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23689600
7.
Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase.
Cancer Sci
; 103(8): 1429-33, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22533343
8.
Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis.
Eur J Neurosci
; 34(8): 1179-88, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21777407
9.
Expansive gene transfer in the rat CNS rapidly produces amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed.
Mol Ther
; 18(12): 2064-74, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20877346
10.
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression.
Mol Ther
; 17(4): 607-13, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19223871
11.
Neuronal susceptibility to beta-amyloid toxicity and ischemic injury involves histone deacetylase-2 regulation of endophilin-B1.
Brain Pathol
; 29(2): 164-175, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30028551
12.
Monophosphoryl lipid A is an lipopolysaccharide-derived Toll-like receptor 4 agonist which may improve Alzheimer's disease pathology.
Expert Opin Biol Ther
; 13(12): 1639-41, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24074146
13.
The advent of AAV9 expands applications for brain and spinal cord gene delivery.
Expert Opin Biol Ther
; 12(6): 757-66, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22519910
14.
Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus.
Exp Neurol
; 233(2): 807-14, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22177996
15.
Transcriptome analysis of a tau overexpression model in rats implicates an early pro-inflammatory response.
Exp Neurol
; 224(1): 197-206, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20346943
16.
Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer.
Neurobiol Aging
; 31(12): 2091-102, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-19155101
17.
Versatile somatic gene transfer for modeling neurodegenerative diseases.
Neurotox Res
; 16(3): 329-42, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19669852