Detalhe da pesquisa
1.
The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.
Mol Cancer
; 20(1): 141, 2021 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34727930
2.
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.
Mol Cancer
; 18(1): 92, 2019 05 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31072393
3.
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.
bioRxiv
; 2023 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37163116
4.
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth.
EMBO Mol Med
; 13(7): e14089, 2021 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34102002
5.
High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer.
Cancer Lett
; 514: 79-89, 2021 08 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34044069
6.
Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein.
Nat Commun
; 12(1): 6941, 2021 12 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34862367
7.
Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function.
Cancer Res
; 80(17): 3568-3579, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32606003
8.
Expression of the Receptor for Hyaluronic Acid-Mediated Motility (RHAMM) in Endometrial Cancer is Associated With Adverse Histologic Parameters and Tumor Progression.
Appl Immunohistochem Mol Morphol
; 28(6): 453-459, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30920393
9.
SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions.
J Cell Biol
; 218(9): 3060-3076, 2019 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31308216
10.
DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis.
Oncogene
; 38(45): 7046-7059, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31409902
11.
Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma.
Mol Oncol
; 13(11): 2441-2459, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31545551
12.
Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.
J Natl Cancer Inst
; 110(4): 390-399, 2018 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29202196
13.
CD70 as a target for chimeric antigen receptor T cells in head and neck squamous cell carcinoma.
Oral Oncol
; 78: 145-150, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29496042
14.
Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
J Cell Biol
; 216(12): 4255-4270, 2017 12 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29114068
15.
DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers.
Oncotarget
; 7(29): 45144-45157, 2016 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27174913
16.
MicroRNA-375 as a biomarker for malignant transformation in oral lesions.
Oral Surg Oral Med Oral Pathol Oral Radiol
; 122(6): 743-752.e1, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27720656
17.
Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma.
Oncotarget
; 7(26): 39957-39969, 2016 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27220886
18.
Studies characterizing 60 kda autoantibodies in subjects with schizophrenia.
Biol Psychiatry
; 53(5): 361-75, 2003 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12614989
19.
CDK5 is a major regulator of the tumor suppressor DLC1.
J Cell Biol
; 207(5): 627-42, 2014 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-25452387
20.
Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-ß signaling to drive malignant progression.
Cancer Res
; 74(7): 2038-49, 2014 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24520074