Detalhe da pesquisa
1.
Molecular recognition of morphine and fentanyl by the human µ-opioid receptor.
Cell
; 185(23): 4361-4375.e19, 2022 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36368306
2.
Dimerization and antidepressant recognition at noradrenaline transporter.
Nature
; 630(8015): 247-254, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38750358
3.
GPCR activation and GRK2 assembly by a biased intracellular agonist.
Nature
; 620(7974): 676-681, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37532940
4.
Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.
Mol Cell
; 77(3): 669-680.e4, 2020 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32004470
5.
Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4.
Nature
; 594(7864): 583-588, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34135510
6.
Identification of CAF-related lncRNAs at the pan-cancer level represents a potential carcinogenic risk.
Hum Mol Genet
; 33(12): 1064-1073, 2024 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38507061
7.
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat Chem Biol
; 20(4): 484-492, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-37945893
8.
LATS2 condensates organize signalosomes for Hippo pathway signal transduction.
Nat Chem Biol
; 20(6): 710-720, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38200110
9.
Activation of the GLP-1 receptor by a non-peptidic agonist.
Nature
; 577(7790): 432-436, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31915381
10.
Structural analysis of the dual agonism at GLP-1R and GCGR.
Proc Natl Acad Sci U S A
; 120(33): e2303696120, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37549266
11.
Structural insights into the interaction of three Y-shaped ligands with PI3Kα.
Proc Natl Acad Sci U S A
; 120(34): e2304071120, 2023 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37585458
12.
Molecular basis of signal transduction mediated by the human GIPR splice variants.
Proc Natl Acad Sci U S A
; 120(41): e2306145120, 2023 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37792509
13.
Single hormone or synthetic agonist induces Gs/Gi coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc Natl Acad Sci U S A
; 120(30): e2216329120, 2023 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37478163
14.
Variation of TaMyb10 and their function on grain color and pre-harvest sprouting resistance of wheat.
Plant J
; 118(5): 1388-1399, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38407913
15.
Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3Kα.
Proc Natl Acad Sci U S A
; 119(46): e2215621119, 2022 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36343266
16.
Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc Natl Acad Sci U S A
; 119(20): e2200155119, 2022 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35561211
17.
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα.
Proc Natl Acad Sci U S A
; 119(38): e2210769119, 2022 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36095215
18.
Abnormal global alternative RNA splicing in COVID-19 patients.
PLoS Genet
; 18(4): e1010137, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35421082
19.
Highly Luminescent Chiral Double π-Helical Nanoribbons.
J Am Chem Soc
; 146(8): 5295-5304, 2024 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38363710
20.
Regulated stepwise ESDPT mechanism associated with chalcogen substitutions in BDIBD derivatives.
Phys Chem Chem Phys
; 26(7): 6335-6344, 2024 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38314844