Pesquisa | Secretaria de Estado da Saúde

1.

Structure-based design of non-hypertrophic apelin receptor modulator.

Wang, Wei-Wei; Ji, Su-Yu; Zhang, Wenjia; Zhang, Junxia; Cai, Chenxi; Hu, Rubi; Zang, Shao-Kun; Miao, Luwei; Xu, Haomang; Chen, Li-Nan; Yang, Zongkuai; Guo, Jia; Qin, Jiao; Shen, Dan-Dan; Liang, Ping; Zhang, Yan; Zhang, Yan.

Cell ; 187(6): 1460-1475.e20, 2024 Mar 14.

Artigo Inglês | MEDLINE | ID: mdl-38428423

2.

Lactate Elicits ER-Mitochondrial Mg²⁺ Dynamics to Integrate Cellular Metabolism.

Daw, Cassidy C; Ramachandran, Karthik; Enslow, Benjamin T; Maity, Soumya; Bursic, Brian; Novello, Matthew J; Rubannelsonkumar, Cherubina S; Mashal, Ayah H; Ravichandran, Joel; Bakewell, Terry M; Wang, Weiwei; Li, Kang; Madaris, Travis R; Shannon, Christopher E; Norton, Luke; Kandala, Soundarya; Caplan, Jeffrey; Srikantan, Subramanya; Stathopulos, Peter B; Reeves, W Brian; Madesh, Muniswamy.

Cell ; 183(2): 474-489.e17, 2020 10 15.

Artigo Inglês | MEDLINE | ID: mdl-33035451

3.

Cryo-EM Structure of the Open Human Ether-à-go-go-Related K⁺ Channel hERG.

Wang, Weiwei; MacKinnon, Roderick.

Cell ; 169(3): 422-430.e10, 2017 04 20.

Artigo Inglês | MEDLINE | ID: mdl-28431243

4.

Conformational transitions and activation of the adhesion receptor CD97.

Mao, Chunyou; Zhao, Ru-Jia; Dong, Ying-Jun; Gao, Mingxin; Chen, Li-Nan; Zhang, Chao; Xiao, Peng; Guo, Jia; Qin, Jiao; Shen, Dan-Dan; Ji, Su-Yu; Zang, Shao-Kun; Zhang, Huibing; Wang, Wei-Wei; Shen, Qingya; Sun, Jin-Peng; Zhang, Yan.

Mol Cell ; 84(3): 570-583.e7, 2024 Feb 01.

Artigo Inglês | MEDLINE | ID: mdl-38215752

5.

Structure of the human ATP synthase.

Lai, Yuezheng; Zhang, Yuying; Zhou, Shan; Xu, Jinxu; Du, Zhanqiang; Feng, Ziyan; Yu, Long; Zhao, Ziqing; Wang, Weiwei; Tang, Yanting; Yang, Xiuna; Guddat, Luke W; Liu, Fengjiang; Gao, Yan; Rao, Zihe; Gong, Hongri.

Mol Cell ; 83(12): 2137-2147.e4, 2023 Jun 15.

Artigo Inglês | MEDLINE | ID: mdl-37244256

6.

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24.

Chong, Wai Po; Mattapallil, Mary J; Raychaudhuri, Kumarkrishna; Bing, So Jin; Wu, Sihan; Zhong, Yajie; Wang, WeiWei; Chen, Zilin; Silver, Phyllis B; Jittayasothorn, Yingyos; Chan, Chi-Chao; Chen, Jun; Horai, Reiko; Caspi, Rachel R.

Immunity ; 53(2): 384-397.e5, 2020 08 18.

Artigo Inglês | MEDLINE | ID: mdl-32673565

7.

Salmonella manipulates macrophage migration via SteC-mediated myosin light chain activation to penetrate the gut-vascular barrier.

Dai, Yuanji; Zhang, Min; Liu, Xiaoyu; Sun, Ting; Qi, Wenqi; Ding, Wei; Chen, Zhe; Zhang, Ping; Liu, Ruirui; Chen, Huimin; Chen, Siyan; Wang, Yuzhen; Yue, Yingying; Song, Nannan; Wang, Weiwei; Jia, Haihong; Ma, Zhongrui; Li, Cuiling; Chen, Qixin; Li, Bingqing.

EMBO J ; 43(8): 1499-1518, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38528181

8.

Enantiomer-dependent immunological response to chiral nanoparticles.

Xu, Liguang; Wang, Xiuxiu; Wang, Weiwei; Sun, Maozhong; Choi, Won Jin; Kim, Ji-Young; Hao, Changlong; Li, Si; Qu, Aihua; Lu, Meiru; Wu, Xiaoling; Colombari, Felippe M; Gomes, Weverson R; Blanco, Asdrubal L; de Moura, Andre F; Guo, Xiao; Kuang, Hua; Kotov, Nicholas A; Xu, Chuanlai.

Nature ; 601(7893): 366-373, 2022 01.

Artigo Inglês | MEDLINE | ID: mdl-35046606

9.

CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis.

Yuan, Youwen; Li, Kangli; Ye, Xueru; Wen, Shiyi; Zhang, Yanan; Teng, Fei; Zhou, Xuan; Deng, Yajuan; Yang, Xiaoyu; Wang, Weiwei; Lin, Jiayang; Luo, Shenjian; Zhang, Peizhen; Shi, Guojun; Zhang, Huijie.

Proc Natl Acad Sci U S A ; 121(3): e2310711121, 2024 Jan 16.

Artigo Inglês | MEDLINE | ID: mdl-38190531

10.

Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance.

Lee, Heon-Woo; Xu, Yanying; Zhu, Xiaolong; Jang, Cholsoon; Choi, Woosoung; Bae, Hosung; Wang, Weiwei; He, Liqun; Jin, Suk-Won; Arany, Zoltan; Simons, Michael.

EMBO J ; 41(9): e109890, 2022 05 02.

Artigo Inglês | MEDLINE | ID: mdl-35243676

11.

Structure of the human respiratory complex II.

Du, Zhanqiang; Zhou, Xiaoting; Lai, Yuezheng; Xu, Jinxu; Zhang, Yuying; Zhou, Shan; Feng, Ziyan; Yu, Long; Tang, Yanting; Wang, Weiwei; Yu, Lu; Tian, Changlin; Ran, Ting; Chen, Hongming; Guddat, Luke W; Liu, Fengjiang; Gao, Yan; Rao, Zihe; Gong, Hongri.

Proc Natl Acad Sci U S A ; 120(18): e2216713120, 2023 05 02.

Artigo Inglês | MEDLINE | ID: mdl-37098072

12.

Fine-tuning an aromatic ring-hydroxylating oxygenase to degrade high molecular weight polycyclic aromatic hydrocarbon.

Guo, Lihua; Ouyang, Xingyu; Wang, Weiwei; Qiu, Xiaoyu; Zhao, Yi-Lei; Xu, Ping; Tang, Hongzhi.

J Biol Chem ; : 107343, 2024 May 03.

Artigo Inglês | MEDLINE | ID: mdl-38705395

13.

The structure of the archaeal nuclease RecJ2 implicates its catalytic mechanism and inability to interact with GINS.

Wang, Wei-Wei; Yi, Gang-Shun; Zhou, Huan; Zhao, Yi-Xuan; Wang, Qi-Sheng; He, Jian-Hua; Yu, Feng; Xiao, Xiang; Liu, Xi-Peng.

J Biol Chem ; : 107379, 2024 May 16.

Artigo Inglês | MEDLINE | ID: mdl-38762184

14.

Identifying the potential miRNA biomarkers based on multi-view networks and reinforcement learning for diseases.

Su, Benzhe; Wang, Weiwei; Lin, Xiaohui; Liu, Shenglan; Huang, Xin.

Brief Bioinform ; 25(1)2023 11 22.

Artigo Inglês | MEDLINE | ID: mdl-38018913

15.

Computational Pathology for Prediction of Isocitrate Dehydrogenase Gene Mutation from Whole Slide Images in Adult Patients with Diffuse Glioma.

Zhao, Yuanshen; Wang, Weiwei; Ji, Yuchen; Guo, Yang; Duan, Jingxian; Liu, Xianzhi; Yan, Dongming; Liang, Dong; Li, Wencai; Zhang, Zhenyu; Li, Zhi-Cheng.

Am J Pathol ; 194(5): 747-758, 2024 May.

Artigo Inglês | MEDLINE | ID: mdl-38325551

16.

Dynamic alternations of interhemispheric functional connectivity in brachial plexus avulsion injury patients with nerve transfer: a resting state fMRI study.

Yang, Yang; Li, Tie; Deng, Yan; Wang, Junlong; Li, Yajie; Liu, Hanqiu; Wang, Weiwei.

Cereb Cortex ; 34(1)2024 01 14.

Artigo Inglês | MEDLINE | ID: mdl-37955665

17.

Epigenomic analysis of the myometrium during late implantation revealed regulatory elements in genes related to the cellular zinc homeostasis pathway in pigs.

Wang, Weiwei; Sun, Yan; Xu, Pengfei; Liang, Hao; Wang, Yue; Deng, Dadong; Cao, Jianhua; Yu, Mei.

Genomics ; 116(1): 110768, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-38128703

18.

Coordination between two cis-elements of WRKY33, bound by the same transcription factor, confers humid adaption in Arabidopsis thaliana.

Liu, Bao; Zheng, Yudan; Lou, Shangling; Liu, Meng; Wang, Weiwei; Feng, Xiaoqin; Zhang, Han; Song, Yan; Liu, Huanhuan.

Plant Mol Biol ; 114(2): 30, 2024 Mar 19.

Artigo Inglês | MEDLINE | ID: mdl-38503847

19.

Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.

Pan, Zhenguo; Yu, Xiaoyu; Wang, Weiwei; Shen, Kai; Chen, Jianwei; Zhang, Yunfeng; Huang, Rongrong.

J Neurochem ; 2024 May 17.

Artigo Inglês | MEDLINE | ID: mdl-38761015

20.

Establishment of patient-derived organoids for guiding personalized therapies in breast cancer patients.

Wu, Huizi; Wang, Weiwei; Zhang, Yinbin; Chen, Yinxi; Shan, Changyou; Li, Jia; Jia, Yiwei; Li, Chaofan; Du, Chong; Cai, Yifan; Zhang, Yu; Zhang, Shuqun; Wu, Fei.

Int J Cancer ; 155(2): 324-338, 2024 Jul 15.

Artigo Inglês | MEDLINE | ID: mdl-38533706

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