Detalhe da pesquisa
1.
Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response.
Br J Cancer
; 125(12): 1666-1676, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34663950
2.
An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice.
Hum Mutat
; 39(3): 394-405, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29215764
3.
Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.
FASEB J
; 29(4): 1426-34, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25550458
4.
AmpliVar: mutation detection in high-throughput sequence from amplicon-based libraries.
Hum Mutat
; 36(4): 411-8, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25664426
5.
Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice.
Biochem J
; 458(2): 251-8, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24320611
6.
Mutation detection by clonal sequencing of PCR amplicons and grouped read typing is applicable to clinical diagnostics.
Hum Mutat
; 34(1): 248-54, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-22915446
7.
Optimizing Amplification of the GC-Rich TERT Promoter Region Using 7-Deaza-dGTP for Droplet Digital PCR Quantification of TERT Promoter Mutations.
Clin Chem
; 64(4): 745-747, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29382647
8.
Minimizing Sample Failure Rates for Challenging Clinical Tumor Samples.
J Mol Diagn
; 25(5): 263-273, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36773702
9.
Epitope Lability of Phosphorylated Biomarkers of the DNA Damage Response Pathway Results in Increased Vulnerability to Effects of Delayed or Incomplete Formalin Fixation.
J Histochem Cytochem
; 71(5): 237-257, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37119278
10.
Menin and p53 have non-synergistic effects on tumorigenesis in mice.
BMC Cancer
; 12: 252, 2012 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-22708734
11.
Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling.
Gastroenterology
; 137(3): 902-13, 913.e1-11, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19454286
12.
13.
Clinical Utility of Real-Time Targeted Molecular Profiling in the Clinical Management of Ovarian Cancer: The ALLOCATE Study.
JCO Precis Oncol
; 3: 1-18, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-35100705
14.
PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein.
Neuro Oncol
; 20(10): 1344-1355, 2018 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29718345
15.
Cetuximab Alone or With Irinotecan for Resistant KRAS-, NRAS-, BRAF- and PIK3CA-wild-type Metastatic Colorectal Cancer: The AGITG Randomized Phase II ICECREAM Study.
Clin Colorectal Cancer
; 17(4): 313-319, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30463680
16.
An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin.
Cancer Res
; 65(10): 4031-40, 2005 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15899792
17.
Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies.
Oncotarget
; 7(41): 66569-66585, 2016 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27611953
18.
Response to Cetuximab With or Without Irinotecan in Patients With Refractory Metastatic Colorectal Cancer Harboring the KRAS G13D Mutation: Australasian Gastro-Intestinal Trials Group ICECREAM Study.
J Clin Oncol
; 34(19): 2258-64, 2016 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27114605
19.
High-Throughput Amplicon-Based Copy Number Detection of 11 Genes in Formalin-Fixed Paraffin-Embedded Ovarian Tumour Samples by MLPA-Seq.
PLoS One
; 10(11): e0143006, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26569395
20.
Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.
Mol Cancer Ther
; 13(2): 468-74, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24398427