Detalhe da pesquisa
1.
Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo.
Drug Metab Dispos
; 51(7): 851-861, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37055191
2.
Determination of Real Time in Vivo Drug Receptor Occupancy for a Covalent Binding Drug as a Clinical Pharmacodynamic Biomarker by Immunocapture-LC-MS/MS.
Anal Chem
; 91(13): 8443-8452, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31247719
3.
Determination of the molecular weight of poly(ethylene glycol) in biological samples by reversed-phase LC-MS with in-source fragmentation.
Anal Bioanal Chem
; 405(12): 4283-7, 2013 May.
Artigo
Inglês
| MEDLINE | ID: mdl-23430183
4.
Bicyclic Ligand-Biased Agonists of S1P1: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles.
J Med Chem
; 64(3): 1454-1480, 2021 02 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33492963
5.
Disposition of [1'-(14)C]stavudine after oral administration to humans.
Drug Metab Dispos
; 38(4): 655-66, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20053818
6.
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates.
J Med Chem
; 63(22): 13913-13950, 2020 11 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33155811
7.
Normalization strategies for metabonomic analysis of urine samples.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(5-6): 547-52, 2009 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19185549
8.
Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance.
PLoS One
; 14(3): e0212670, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30913212
9.
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials.
J Med Chem
; 62(5): 2265-2285, 2019 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30785748
10.
Utility of the hybrid LTQ-FTMS for drug metabolism applications.
Curr Drug Metab
; 7(5): 547-55, 2006 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-16787162
11.
Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.
ACS Med Chem Lett
; 7(1): 40-5, 2016 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26819663
12.
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P1 Receptor Modulator.
J Med Chem
; 59(24): 11138-11147, 2016 12 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28002964
13.
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design.
J Med Chem
; 59(21): 9837-9854, 2016 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27726358
14.
Addressing drug effects on cut point determination for an anti-drug antibody assay.
J Immunol Methods
; 384(1-2): 152-6, 2012 Oct 31.
Artigo
Inglês
| MEDLINE | ID: mdl-22750627
15.
Characterization of protein therapeutics by mass spectrometry: recent developments and future directions.
Drug Discov Today
; 16(1-2): 58-64, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21093608
16.
A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins.
J Am Soc Mass Spectrom
; 21(5): 837-44, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20189823