Detalhe da pesquisa
1.
Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice.
Hum Mol Genet
; 29(2): 202-215, 2020 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31696228
2.
QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.
Proc Natl Acad Sci U S A
; 115(37): E8652-E8659, 2018 09 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30154163
3.
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.
Commun Biol
; 5(1): 1066, 2022 10 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36207580
4.
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.
Nat Neurosci
; 25(2): 226-237, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35115730
5.
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
iScience
; 24(11): 103221, 2021 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34746695
6.
A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules.
Sci Rep
; 10(1): 954, 2020 01 22.
Artigo
Inglês
| MEDLINE | ID: mdl-31969612
7.
Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation.
Stem Cell Reports
; 14(3): 406-419, 2020 03 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32109367
8.
Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.
Nat Commun
; 8(1): 623, 2017 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28931805