Detalhe da pesquisa
1.
A phase 1 trial of the MEK inhibitor selumetinib in combination with pembrolizumab for advanced or metastatic solid tumors.
Invest New Drugs
; 2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38483782
2.
Results of an open-label phase 1b study of the ERK inhibitor MK-8353 plus the MEK inhibitor selumetinib in patients with advanced or metastatic solid tumors.
Invest New Drugs
; 41(3): 380-390, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37040046
3.
Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.
J Virol
; 94(13)2020 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32295913
4.
Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.
Lancet Oncol
; 19(7): 940-952, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29875066
5.
International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology.
Pharmacol Rev
; 64(3): 389-420, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22759794
6.
Biomarkers predictive of response to pembrolizumab in head and neck cancer.
Cancer Med
; 12(6): 6603-6614, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36479637
7.
Baseline and post-treatment biomarkers of resistance to anti-PD-1 therapy in acral and mucosal melanoma: an observational study.
J Immunother Cancer
; 10(7)2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35793874
8.
Pharmacological validation of candidate causal sleep genes identified in an N2 cross.
J Neurogenet
; 25(4): 167-81, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22091728
9.
Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.
Sci Rep
; 10(1): 8374, 2020 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32409700
10.
Fine-Needle Aspiration for the Evaluation of Hepatic Pharmacokinetics of Vaniprevir: A Randomized Trial in Patients With Hepatitis C Virus Infection.
Clin Pharmacol Ther
; 107(6): 1325-1333, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31868916
11.
Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy.
Science
; 362(6411)2018 10 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30309915
12.
Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation.
Antiviral Res
; 139: 161-170, 2017 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-27889530
13.
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.
Sci Rep
; 7(1): 17193, 2017 12 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29222421
14.
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease.
Invest Ophthalmol Vis Sci
; 47(8): 3603-11, 2006 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16877435
15.
Dual role of Nr2e3 in photoreceptor development and maintenance.
Exp Eye Res
; 87(1): 35-48, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18547563
16.
Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand.
Bioorg Med Chem Lett
; 16(19): 5001-4, 2006 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16879962