Detalhe da pesquisa
1.
Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor.
Bioorg Med Chem Lett
; 21(20): 6188-94, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21903390
2.
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists.
Bioorg Med Chem Lett
; 19(1): 158-62, 2009 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19019676
3.
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.
J Med Chem
; 50(26): 6519-34, 2007 Dec 27.
Artigo
Inglês
| MEDLINE | ID: mdl-18038970
4.
Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.
J Med Chem
; 46(21): 4428-49, 2003 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-14521407
5.
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.
J Med Chem
; 45(1): 1-18, 2002 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-11754575
6.
Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates.
Org Lett
; 10(18): 4117-20, 2008 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-18722456
7.
Pyrrolidine-5,5-trans-lactams as novel mechanism-based inhibitors of human cytomegalovirus protease. Part 3: potency and plasma stability.
Bioorg Med Chem Lett
; 12(13): 1719-22, 2002 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-12067545
8.
Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives.
Bioorg Med Chem Lett
; 12(10): 1405-11, 2002 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-11992787