Detalhe da pesquisa
1.
Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.
Cell
; 154(5): 1085-1099, 2013 Aug 29.
Artigo
Inglês
| MEDLINE | ID: mdl-23954414
2.
A Balancing Act: Learning from the Past to Build a Future-Focused Opioid Strategy.
Annu Rev Physiol
; 86: 1-25, 2024 Feb 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38029388
3.
Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination.
J Neurosci
; 36(30): 7925-35, 2016 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-27466337
4.
Loss of D2 dopamine receptor function modulates cocaine-induced glutamatergic synaptic potentiation in the ventral tegmental area.
J Neurosci
; 33(30): 12329-36, 2013 Jul 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23884939
5.
Intestinal epithelial cell-derived µ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling.
Am J Pathol
; 182(3): 776-85, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23291213
6.
Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic voluntary morphine.
bioRxiv
; 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38659831
7.
Deletion of arrestin-3 does not improve compulsive drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration.
bioRxiv
; 2024 Mar 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38562752
8.
Trafficking properties of the D5 dopamine receptor.
Traffic
; 12(5): 644-56, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21348911
9.
Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling.
J Pharmacol Exp Ther
; 344(1): 179-88, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23097213
10.
Arrestin-3 Agonism at Dopamine D3 Receptors Defines a Subclass of Second-Generation Antipsychotics That Promotes Drug Tolerance.
Biol Psychiatry
; 94(7): 531-542, 2023 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36931452
11.
The G-protein coupled receptor associated sorting protein GASP-1 regulates the signalling and trafficking of the viral chemokine receptor US28.
Traffic
; 11(5): 660-74, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20102549
12.
Dopamine D(3) receptors are down-regulated following heterologous endocytosis by a specific interaction with G protein-coupled receptor-associated sorting protein-1.
J Biol Chem
; 286(2): 1598-608, 2011 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-21030592
13.
The chemoselective reactions of tyrosine-containing G-protein-coupled receptor peptides with [Cp*Rh(H2O)3](OTf)2, including 2D NMR structures and the biological consequences.
J Am Chem Soc
; 134(25): 10321-4, 2012 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-22671299
14.
Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice.
J Pharmacol Exp Ther
; 340(2): 386-92, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22062352
15.
Functional characterization of human variants of the mu-opioid receptor gene.
Proc Natl Acad Sci U S A
; 106(26): 10811-6, 2009 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19528663
16.
Opioid-Induced GABA potentiation after chronic morphine attenuates the rewarding effects of opioids in the ventral tegmental area.
J Neurosci
; 30(42): 14029-35, 2010 Oct 20.
Artigo
Inglês
| MEDLINE | ID: mdl-20962224
17.
micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal.
J Neurosci
; 30(9): 3276-86, 2010 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-20203187
18.
Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence.
Curr Biol
; 18(2): 129-35, 2008 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-18207746
19.
Heteromerization of the µ- and δ-opioid receptors produces ligand-biased antagonism and alters µ-receptor trafficking.
J Pharmacol Exp Ther
; 337(3): 868-75, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21422164
20.
A novel knock-in mouse reveals mechanistically distinct forms of morphine tolerance.
J Pharmacol Exp Ther
; 338(2): 633-40, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21562138