Detalhe da pesquisa
1.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Cell
; 161(6): 1252-65, 2015 Jun 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26046436
2.
Revisiting the ß-Lactams for Tuberculosis Therapy with a Compound-Compound Synthetic Lethality Approach.
Antimicrob Agents Chemother
; 63(11)2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31427291
3.
Identification of Small Molecule Inhibitors of Human Cytochrome c Oxidase That Target Chemoresistant Glioma Cells.
J Biol Chem
; 291(46): 24188-24199, 2016 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27679486
4.
Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.
Am J Respir Crit Care Med
; 194(9): 1092-1103, 2016 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27104944
5.
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
Biochem J
; 473(8): 1027-35, 2016 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26846349
6.
Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.
J Biol Chem
; 290(16): 10504-17, 2015 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-25724652
7.
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
PLoS Pathog
; 10(6): e1004213, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24967809
8.
Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.
J Biol Chem
; 289(47): 32937-51, 2014 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25228699
9.
A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus.
Virol J
; 10: 19, 2013 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-23302182
10.
NIH: translation centre bridges a gap.
Nature
; 474(7350): 161, 2011 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21654789
11.
A high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio cholerae.
Antimicrob Agents Chemother
; 55(9): 4134-43, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21709090
12.
Identification of novel small molecule activators of nuclear factor-κB with neuroprotective action via high-throughput screening.
J Neurosci Res
; 89(1): 58-72, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-21046675
13.
Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.
Bioorg Med Chem
; 19(23): 7120-8, 2011 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22024272
14.
A high-throughput screen for chemical inhibitors of exocytic transport in yeast.
Chembiochem
; 11(9): 1291-301, 2010 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-20461743
15.
HTS-driven discovery of new chemotypes with West Nile Virus inhibitory activity.
Molecules
; 15(3): 1690-704, 2010 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-20336008
16.
Identification of Specific and Nonspecific Inhibitors of Bacillus anthracis Typeâ III Pantothenate Kinase (PanK).
ChemMedChem
; 14(1): 78-82, 2019 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30376607
17.
High-throughput screening of a 100,000-compound library for inhibitors of influenza A virus (H3N2).
J Biomol Screen
; 13(9): 879-87, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18812571
18.
Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits.
Bioorg Med Chem
; 16(7): 4138-49, 2008 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18343121
19.
Development and validation of a high-throughput screen for inhibitors of SARS CoV and its application in screening of a 100,000-compound library.
J Biomol Screen
; 12(1): 33-40, 2007 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17200104
20.
A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase.
J Biomol Screen
; 12(1): 100-5, 2007 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17175524