Detalhe da pesquisa
1.
Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours.
Xenobiotica
; 50(7): 793-804, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-31847673
2.
Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors.
Oncology
; 91(5): 251-260, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27598338
3.
Impact of Repeated Tail Clip and Saphenous Vein Phlebotomy on Rats Used in Toxicology Studies.
Toxicol Pathol
; 44(7): 1013-20, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27381889
4.
Evaluation and Optimization of Blood Micro-Sampling Methods: Serial Sampling in a Cross-Over Design from an Individual Mouse.
J Pharm Pharm Sci
; 19(4): 496-510, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28057168
5.
Phase I dose escalation and pharmacokinetic evaluation of two different schedules of LY2334737, an oral gemcitabine prodrug, in patients with advanced solid tumors.
Invest New Drugs
; 33(6): 1206-16, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26377590
6.
Evaluation of the likelihood of a selective CHK1 inhibitor (LY2603618) to inhibit CYP2D6 with desipramine as a probe substrate in cancer patients.
Biopharm Drug Dispos
; 36(1): 49-63, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25296725
7.
Fully-automated approach for online dried blood spot extraction and bioanalysis by two-dimensional-liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry.
Anal Chem
; 86(2): 1246-53, 2014 Jan 21.
Artigo
Inglês
| MEDLINE | ID: mdl-24364804
8.
Automated high-capacity on-line extraction and bioanalysis of dried blood spot samples using liquid chromatography/high-resolution accurate mass spectrometry.
Rapid Commun Mass Spectrom
; 28(22): 2415-26, 2014 Nov 30.
Artigo
Inglês
| MEDLINE | ID: mdl-25303470
9.
Disposition and metabolism of LY2603618, a Chk-1 inhibitor following intravenous administration in patients with advanced and/or metastatic solid tumors.
Xenobiotica
; 44(9): 827-41, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24666335
10.
Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase.
Drug Metab Dispos
; 41(3): 541-5, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23230131
11.
Microsampling in pediatric studies: pharmacokinetic sampling for baricitinib (Olumiant™) in global pediatric studies.
Bioanalysis
; 15(11): 621-636, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37293791
12.
Standard Venipuncture vs a Capillary Blood Collection Device for the Prospective Determination of Abnormal Liver Chemistry.
J Appl Lab Med
; 8(3): 535-550, 2023 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36533519
13.
Quantification of abemaciclib and metabolites: evolution of bioanalytical methods supporting a novel oncolytic agent.
Bioanalysis
; 13(9): 711-724, 2021 May.
Artigo
Inglês
| MEDLINE | ID: mdl-33870730
14.
Lessons learned from the COVID-19 pandemic and its impact on bioanalysis and drug development.
Bioanalysis
; 13(15): 1205-1211, 2021 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-34275332
15.
The effectiveness of quality control samples in pharmaceutical bioanalysis.
Bioanalysis
; 13(3): 135-145, 2021 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-33538614
16.
Quantification of gemcitabine incorporation into human DNA by LC/MS/MS as a surrogate measure for target engagement.
Anal Chem
; 82(15): 6576-83, 2010 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20698580
17.
Evaluation of correlation between bioanalytical methods.
Bioanalysis
; 12(6): 419-426, 2020 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-32285680
18.
Land O'Lakes Workshop on Microsampling: Enabling Broader Adoption.
AAPS J
; 22(6): 135, 2020 10 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33098040
19.
Recommendations for singlet-based approach in ligand binding assays: an IQ Consortium perspective.
Bioanalysis
; 12(12): 823-834, 2020 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-32558588
20.
Microsampling for quantitative bioanalysis, an industry update: output from an AAPS/EBF survey.
Bioanalysis
; 11(7): 619-628, 2019 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-30973016