Pesquisa | Secretaria de Estado da Saúde

1.

Comparison of Whole-Genome Sequence-Based Methods and PCR Ribotyping for Subtyping of Clostridioides difficile.

Baktash, A; Corver, J; Harmanus, C; Smits, W K; Fawley, W; Wilcox, M H; Kumar, N; Eyre, D W; Indra, A; Mellmann, A; Kuijper, E J.

J Clin Microbiol ; 60(2): e0173721, 2022 02 16.

Artigo Inglês | MEDLINE | ID: mdl-34911367

2.

Protecting the Microbiota.

Rooney, C M; Ahmed, S; Wilcox, M H.

J Infect Dis ; 223(12 Suppl 2): S290-S295, 2021 06 16.

Artigo Inglês | MEDLINE | ID: mdl-33838031

3.

Investigation of the effect of the adsorbent DAV131A on the propensity of moxifloxacin to induce simulated Clostridioides (Clostridium) difficile infection (CDI) in an in vitro human gut model.

Chilton, C H; Crowther, G S; Miossec, C; de Gunzburg, J; Andremont, A; Wilcox, M H.

J Antimicrob Chemother ; 75(6): 1458-1465, 2020 06 01.

Artigo Inglês | MEDLINE | ID: mdl-32097465

4.

Effect of fluoroquinolone resistance mutation Thr-82âIle on Clostridioides difficile fitness.

Vernon, J J; Wilcox, M H; Freeman, J.

J Antimicrob Chemother ; 74(4): 877-884, 2019 04 01.

Artigo Inglês | MEDLINE | ID: mdl-30590496

5.

Dissemination of multiple carbapenem resistance genes in an in vitro gut model simulating the human colon.

Rooney, C M; Sheppard, A E; Clark, E; Davies, K; Hubbard, A T M; Sebra, R; Crook, D W; Walker, A S; Wilcox, M H; Chilton, C H.

J Antimicrob Chemother ; 74(7): 1876-1883, 2019 07 01.

Artigo Inglês | MEDLINE | ID: mdl-30989197

6.

Biofilm-derived spores of Clostridioides (Clostridium) difficile exhibit increased thermotolerance compared to planktonic spores.

Pickering, D S; Wilcox, M H; Chilton, C H.

Anaerobe ; 54: 169-171, 2018 Dec.

Artigo Inglês | MEDLINE | ID: mdl-30292821

7.

Investigating the effect of supplementation on Clostridioides (Clostridium) difficile spore recovery in two solid agars.

Pickering, D S; Vernon, J J; Freeman, J; Wilcox, M H; Chilton, C H.

Anaerobe ; 50: 38-43, 2018 Apr.

Artigo Inglês | MEDLINE | ID: mdl-29408598

8.

Protective antibodies against Clostridium difficile are present in intravenous immunoglobulin and are retained in humans following its administration.

Negm, O H; MacKenzie, B; Hamed, M R; Ahmad, O A J; Shone, C C; Humphreys, D P; Ravi Acharya, K; Loscher, C E; Marszalowska, I; Lynch, M; Wilcox, M H; Monaghan, T M.

Clin Exp Immunol ; 188(3): 437-443, 2017 06.

Artigo Inglês | MEDLINE | ID: mdl-28213939

9.

Evaluation of the novel artus C. difficile QS-RGQ, VanR QS-RGQ and MRSA/SA QS-RGQ assays for the laboratory diagnosis of Clostridium difficile infection (CDI), and for vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) screening.

Morris, K A; Macfarlane-Smith, L R; Wilcox, M H.

Eur J Clin Microbiol Infect Dis ; 36(5): 823-829, 2017 May.

Artigo Inglês | MEDLINE | ID: mdl-27987047

10.

Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of C. difficile infection (CDI)?

Berry, C E; Davies, K A; Owens, D W; Wilcox, M H.

Eur J Clin Microbiol Infect Dis ; 36(12): 2405-2415, 2017 Dec.

Artigo Inglês | MEDLINE | ID: mdl-28780742

11.

Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection.

Chilton, C H; Crowther, G S; Spiewak, K; Brindell, M; Singh, G; Wilcox, M H; Monaghan, T M.

J Antimicrob Chemother ; 71(4): 975-85, 2016 Apr.

Artigo Inglês | MEDLINE | ID: mdl-26759363

12.

Molecular characterisation of Czech Clostridium difficile isolates collected in 2013-2015.

Krutova, M; Nyc, O; Matejkova, J; Allerberger, F; Wilcox, M H; Kuijper, E J.

Int J Med Microbiol ; 306(7): 479-485, 2016 Nov.

Artigo Inglês | MEDLINE | ID: mdl-27519407

13.

Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID).

Davies, K; Davis, G; Barbut, F; Eckert, C; Petrosillo, N; Wilcox, M H.

Eur J Clin Microbiol Infect Dis ; 35(12): 1949-1956, 2016 Dec.

Artigo Inglês | MEDLINE | ID: mdl-27590621

14.

Predominance of Clostridium difficile ribotypes 012, 027 and 046 in a university hospital in Chile, 2012.

Plaza-Garrido, Á; Barra-Carrasco, J; Macias, J H; Carman, R; Fawley, W N; Wilcox, M H; Hernández-Rocha, C; Guzmán-Durán, A M; Alvarez-Lobos, M; Paredes-Sabja, D.

Epidemiol Infect ; 144(5): 976-9, 2016 Apr.

Artigo Inglês | MEDLINE | ID: mdl-26489717

15.

Comparison of the Vidas C. difficile GDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluD for Detection of Clostridium difficile in Fecal Samples.

Davies, K A; Berry, C E; Morris, K A; Smith, R; Young, S; Davis, T E; Fuller, D D; Buckner, R J; Wilcox, M H.

J Clin Microbiol ; 53(6): 1931-4, 2015 Jun.

Artigo Inglês | MEDLINE | ID: mdl-25788549

16.

SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model.

Baines, S D; Crowther, G S; Freeman, J; Todhunter, S; Vickers, R; Wilcox, M H.

J Antimicrob Chemother ; 70(1): 182-9, 2015 Jan.

Artigo Inglês | MEDLINE | ID: mdl-25190720

17.

Efficacy of alternative fidaxomicin dosing regimens for treatment of simulated Clostridium difficile infection in an in vitro human gut model.

Chilton, C H; Crowther, G S; Todhunter, S L; Ashwin, H; Longshaw, C M; Karas, A; Wilcox, M H.

J Antimicrob Chemother ; 70(9): 2598-607, 2015 Sep.

Artigo Inglês | MEDLINE | ID: mdl-26078392

18.

In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile.

Corbett, D; Wise, A; Birchall, S; Warn, P; Baines, S D; Crowther, G; Freeman, J; Chilton, C H; Vernon, J; Wilcox, M H; Vickers, R J.

J Antimicrob Chemother ; 70(6): 1751-6, 2015.

Artigo Inglês | MEDLINE | ID: mdl-25652750

19.

Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.

Eyre, D W; Tracey, L; Elliott, B; Slimings, C; Huntington, P G; Stuart, R L; Korman, T M; Kotsiou, G; McCann, R; Griffiths, D; Fawley, W N; Armstrong, P; Dingle, K E; Walker, A S; Peto, T E; Crook, D W; Wilcox, M H; Riley, T V.

Euro Surveill ; 20(10): 21059, 2015 Mar 12.

Artigo Inglês | MEDLINE | ID: mdl-25788254

20.

Successful treatment of simulated Clostridium difficile infection in a human gut model by fidaxomicin first line and after vancomycin or metronidazole failure.

Chilton, C H; Crowther, G S; Freeman, J; Todhunter, S L; Nicholson, S; Longshaw, C M; Wilcox, M H.

J Antimicrob Chemother ; 69(2): 451-62, 2014 Feb.

Artigo Inglês | MEDLINE | ID: mdl-24003182

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