Detalhe da pesquisa
1.
Improved green and red GRAB sensors for monitoring dopaminergic activity in vivo.
Nat Methods
; 21(4): 680-691, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38036855
2.
Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2I212F.
Mol Pharmacol
; 103(3): 188-198, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36456191
3.
Discovery and characterization of antimycobacterial nitro-containing compounds with distinct mechanisms of action and in vivo efficacy.
Antimicrob Agents Chemother
; 67(9): e0047423, 2023 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37610224
4.
Agonist-Specific Regulation of G Protein-Coupled Receptors after Chronic Opioid Treatment.
Mol Pharmacol
; 101(5): 300-308, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35193934
5.
Co-activation of GPCRs facilitate GIRK-dependent current.
J Physiol
; 600(22): 4881-4895, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36121348
6.
The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area.
Annu Rev Physiol
; 80: 219-241, 2018 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28938084
7.
A Gain-of-Function Variant in Dopamine D2 Receptor and Progressive Chorea and Dystonia Phenotype.
Mov Disord
; 36(3): 729-739, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33200438
8.
Chronic Treatment with Morphine Disrupts Acute Kinase-Dependent Desensitization of GPCRs.
Mol Pharmacol
; 98(4): 497-507, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32362586
9.
Recent Progress in Opioid Research from an Electrophysiological Perspective.
Mol Pharmacol
; 98(4): 401-409, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32198208
10.
Separation of Acute Desensitization and Long-Term Tolerance of µ-Opioid Receptors Is Determined by the Degree of C-Terminal Phosphorylation.
Mol Pharmacol
; 96(4): 505-514, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31383769
11.
Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31405862
12.
Cholinergic Interneurons Underlie Spontaneous Dopamine Release in Nucleus Accumbens.
J Neurosci
; 37(8): 2086-2096, 2017 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28115487
13.
Desensitization and Tolerance of Mu Opioid Receptors on Pontine Kölliker-Fuse Neurons.
Mol Pharmacol
; 93(1): 8-13, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29097440
14.
HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29661875
15.
Presynaptic gain control by endogenous cotransmission of dopamine and GABA in the olfactory bulb.
J Neurophysiol
; 117(3): 1163-1170, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28031402
16.
Regulation of µ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.
Pharmacol Rev
; 65(1): 223-54, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23321159
17.
Agonist Binding and Desensitization of the µ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.
Mol Pharmacol
; 88(4): 816-24, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25934731
18.
µ opioid receptor activation hyperpolarizes respiratory-controlling Kölliker-Fuse neurons and suppresses post-inspiratory drive.
J Physiol
; 593(19): 4453-69, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26175072
19.
Increased agonist affinity at the µ-opioid receptor induced by prolonged agonist exposure.
J Neurosci
; 33(9): 4118-27, 2013 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-23447620
20.
Desensitization of functional µ-opioid receptors increases agonist off-rate.
Mol Pharmacol
; 86(1): 52-61, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24748657