Detalhe da pesquisa
1.
A key to unlocking chromatin revealed by complex structures.
Nature
; 573(7774): 355-356, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31530906
2.
The structure of the RbBP5 ß-propeller domain reveals a surface with potential nucleic acid binding sites.
Nucleic Acids Res
; 46(7): 3802-3812, 2018 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29897600
3.
Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells.
Biochem J
; 474(17): 3059-3073, 2017 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28694351
4.
Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks.
Mol Cell
; 33(2): 181-91, 2009 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19187761
5.
A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases.
Nucleic Acids Res
; 42(1): 661-71, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24049080
6.
Sudden death associated with a novel H401Q PRKAG2 mutation.
Europace
; 22(8): 1278, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32215636
7.
Determination of Histone Methyltransferase Structure by Crystallography.
Methods Mol Biol
; 2529: 137-147, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35733014
8.
Methylation and demethylation activities of a C. elegans MLL-like complex attenuate RAS signalling.
Dev Biol
; 341(1): 142-53, 2010 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20188723
9.
Characterization of a novel WDR5-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1.
J Biol Chem
; 285(43): 32967-32976, 2010 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-20716525
10.
Foot-and-mouth disease virus 2C is a hexameric AAA+ protein with a coordinated ATP hydrolysis mechanism.
J Biol Chem
; 285(32): 24347-59, 2010 Aug 06.
Artigo
Inglês
| MEDLINE | ID: mdl-20507978
11.
Engineering heme binding sites in monomeric rop.
J Biol Inorg Chem
; 14(4): 497-505, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19152012
12.
Author Correction: G-tract RNA removes Polycomb repressive complex 2 from genes.
Nat Struct Mol Biol
; 26(12): 1184-1186, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31695189
13.
G-tract RNA removes Polycomb repressive complex 2 from genes.
Nat Struct Mol Biol
; 26(10): 899-909, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31548724
14.
Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1ß1γ1).
Methods Mol Biol
; 1732: 1-14, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29480465
15.
Targeting the JMJD2A histone lysine demethylase.
Nat Struct Mol Biol
; 14(8): 682-4, 2007 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-17676028
16.
Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Science
; 354(6319): 1543, 2016 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28008037
17.
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun
; 7: 11316, 2016 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27121947
18.
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas.
J Med Chem
; 59(21): 9928-9941, 2016 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27739677
19.
Evolving Catalytic Properties of the MLL Family SET Domain.
Structure
; 23(10): 1921-1933, 2015 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26320581
20.
Engineering redox functions in a nucleic acid binding protein.
Chem Commun (Camb)
; (3): 356-7, 2003 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-12613610