Detalhe da pesquisa
1.
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Nat Immunol
; 21(10): 1194-1204, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32895539
2.
Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor.
Immunity
; 54(12): 2795-2811.e9, 2021 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34788601
3.
Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2ß (Group VIA Phospholipase A2).
J Biol Chem
; 291(44): 23268-23281, 2016 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27650501
4.
Group VIA phospholipase A2 mitigates palmitate-induced ß-cell mitochondrial injury and apoptosis.
J Biol Chem
; 289(20): 14194-210, 2014 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-24648512
5.
Group VIA PLA2 (iPLA2ß) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet ß-cell signaling.
J Biol Chem
; 287(8): 5528-41, 2012 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22194610
6.
Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A(2)-VIA (iPLA(2)ß)-knockout mice.
Biochim Biophys Acta
; 1821(9): 1278-86, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22349267
7.
Effects of endoplasmic reticulum stress on group VIA phospholipase A2 in beta cells include tyrosine phosphorylation and increased association with calnexin.
J Biol Chem
; 285(44): 33843-57, 2010 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-20732873
8.
Enterically derived high-density lipoprotein restrains liver injury through the portal vein.
Science
; 373(6553)2021 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34437091
9.
Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA(2)ß (VIA)-deficient mice.
J Lipid Res
; 51(11): 3166-73, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20686114
10.
Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.
Am J Physiol Endocrinol Metab
; 298(6): E1097-114, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20179248
11.
Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells.
Biomolecules
; 10(10)2020 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33080873
12.
B Cell-Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression.
Immunohorizons
; 3(1): 37-44, 2019 01 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31356175
13.
Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations.
Biochim Biophys Acta
; 1580(1): 40-56, 2002 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-11923099
14.
Genetic modulation of islet ß-cell iPLA2ß expression provides evidence for its impact on ß-cell apoptosis and autophagy.
Islets
; 5(1): 29-44, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23411472
15.
Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents.
Oxid Med Cell Longev
; 2012: 989372, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23213352
16.
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
Am J Physiol Endocrinol Metab
; 294(2): E217-29, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17895289
17.
Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations.
Am J Pathol
; 172(2): 406-16, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18202189
18.
Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice.
Am J Pathol
; 172(4): 868-81, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18349124
19.
Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.
J Biol Chem
; 282(37): 27100-27114, 2007 Sep 14.
Artigo
Inglês
| MEDLINE | ID: mdl-17627946
20.
Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.
J Biol Chem
; 281(30): 20958-20973, 2006 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-16732058