Detalhe da pesquisa
1.
Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress.
Proc Natl Acad Sci U S A
; 111(45): 16136-41, 2014 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-25331895
2.
Time to re-engage psychiatric drug discovery by strengthening confidence in preclinical psychopharmacology.
Psychopharmacology (Berl)
; 238(6): 1417-1436, 2021 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-33694032
3.
Challenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective.
Int J Neuropsychopharmacol
; 13(9): 1269-84, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20716397
4.
Repeated effects of asenapine on adrenergic and cholinergic muscarinic receptors.
Int J Neuropsychopharmacol
; 13(3): 405-10, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19835670
5.
Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain.
Synapse
; 63(5): 413-20, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19177511
6.
Multi- and single-target agents for major psychiatric diseases: therapeutic opportunities and challenges.
Curr Opin Investig Drugs
; 9(1): 28-36, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18183529
7.
Differential regional and dose-related effects of asenapine on dopamine receptor subtypes.
Psychopharmacology (Berl)
; 198(1): 103-11, 2008 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18297468
8.
Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia.
Psychopharmacology (Berl)
; 196(3): 417-29, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-17940749
9.
Validation of a rat in vivo [(3)H]M100907 binding assay to determine a translatable measure of 5-HT(2A) receptor occupancy.
Eur J Pharmacol
; 591(1-3): 136-41, 2008 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-18593577
10.
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.
J Med Chem
; 49(14): 4425-36, 2006 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-16821801
11.
Correction to: Time to re-engage psychiatric drug discovery by strengthening confidence in preclinical psychopharmacology.
Psychopharmacology (Berl)
; 238(7): 2045, 2021 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-33999227
12.
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.
Nat Commun
; 7: 11671, 2016 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-27216573
13.
Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.
J Med Chem
; 48(4): 905-8, 2005 Feb 24.
Artigo
Inglês
| MEDLINE | ID: mdl-15715459
14.
Application of cross-species PET imaging to assess neurotransmitter release in brain.
Psychopharmacology (Berl)
; 232(21-22): 4129-57, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25921033
15.
Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders.
Mol Autism
; 5: 38, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25061506
16.
Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors.
PLoS One
; 9(1): e85136, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24465494
17.
Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration.
Neuropharmacology
; 62(3): 1442-52, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21875607
18.
Attenuation of chronic mild stress-induced 'anhedonia' by asenapine is not associated with a 'hedonic' profile in intracranial self-stimulation.
J Psychopharmacol
; 25(10): 1388-98, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20699353
19.
Toward personalized medicine in the neuropsychiatric field.
Int Rev Neurobiol
; 101: 329-49, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-22050858
20.
Modeling treatment-resistant depression.
Neuropharmacology
; 61(3): 408-13, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21356220