Detalhe da pesquisa
1.
Discovery and mechanistic study of Imperatorin that inhibits HBsAg expression and cccDNA transcription.
J Med Virol
; 96(5): e29669, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38773784
2.
Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo.
Pharmacol Res
; 191: 106769, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37061145
3.
Tricin promoted ATG-7 dependent autophagic degradation of α-synuclein and dopamine release for improving cognitive and motor deficits in Parkinson's disease.
Pharmacol Res
; 196: 106874, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37586619
4.
Mutant p53R211* ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response.
Inflamm Res
; 72(12): 2199-2219, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37935918
5.
Naproxen-Derived New Compound Inhibits the NF-κB, MAPK and PI3K/Akt Signaling Pathways Synergistically with Resveratrol in RAW264.7 Cells.
Molecules
; 28(8)2023 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37110629
6.
Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3'-oxindoles] under Microwave Irradiation and Their Anticancer Activity.
Molecules
; 28(18)2023 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37764279
7.
Traditional Patchouli essential oil modulates the host's immune responses and gut microbiota and exhibits potent anti-cancer effects in ApcMin /+ mice.
Pharmacol Res
; 176: 106082, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35032662
8.
The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis.
Pharmacol Res
; 186: 106549, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36368452
9.
SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome.
Clin Sci (Lond)
; 135(12): 1505-1522, 2021 06 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34128977
10.
Potential therapeutic compounds from traditional Chinese medicine targeting endoplasmic reticulum stress to alleviate rheumatoid arthritis.
Pharmacol Res
; 170: 105696, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34052360
11.
Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry.
Pharmacol Res
; 172: 105820, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34403732
12.
Icariin enhances youth-like features by attenuating the declined gut microbiota in the aged mice.
Pharmacol Res
; 168: 105587, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33798737
13.
Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota.
Pharmacol Res
; 170: 105697, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34062240
14.
A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A.
Hepatology
; 69(5): 1885-1902, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30614547
15.
Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds.
Invest New Drugs
; 38(1): 1-9, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30877426
16.
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.
Pharmacol Res
; 153: 104660, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31982489
17.
Method for Quantification of Ribonucleotides and Deoxyribonucleotides in Human Cells Using (Trimethylsilyl)diazomethane Derivatization Followed by Liquid Chromatography-Tandem Mass Spectrometry.
Anal Chem
; 91(1): 1019-1026, 2019 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30525455
18.
SIRT3 restricts hepatitis B virus transcription and replication through epigenetic regulation of covalently closed circular DNA involving suppressor of variegation 3-9 homolog 1 and SET domain containing 1A histone methyltransferases.
Hepatology
; 68(4): 1260-1276, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29624717
19.
Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
Pharmacol Res
; 147: 104396, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31404628
20.
Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer's disease.
Bioorg Chem
; 87: 474-483, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30927588