Detalhe da pesquisa
1.
Regionally selective cardiovascular responses to adenosine A2A and A2B receptor activation.
FASEB J
; 36(4): e22214, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35230706
2.
COVID-19-Induced Myocarditis: Pathophysiological Roles of ACE2 and Toll-like Receptors.
Int J Mol Sci
; 24(6)2023 Mar 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36982447
3.
Role of the Renin-Angiotensin-Aldosterone and Kinin-Kallikrein Systems in the Cardiovascular Complications of COVID-19 and Long COVID.
Int J Mol Sci
; 22(15)2021 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34361021
4.
Effects of 4 multitargeted receptor tyrosine kinase inhibitors on regional hemodynamics in conscious, freely moving rats.
FASEB J
; 31(3): 1193-1203, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-27986807
5.
Novel selective ß1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease.
FASEB J
; 31(7): 3150-3166, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28400472
6.
Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2.
Int J Mol Sci
; 19(4)2018 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29690653
7.
A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.
Mol Pharmacol
; 88(3): 589-95, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25972446
8.
Mechano-sensitivity of ß2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists.
Commun Biol
; 7(1): 417, 2024 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38580813
9.
Characterisation of tyrosine kinase inhibitor-receptor interactions at VEGFR2 using sunitinib-red and nanoBRET.
Biochem Pharmacol
; 214: 115672, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37406966
10.
Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells.
iScience
; 26(7): 107232, 2023 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37496673
11.
Role of endothelin ETA receptors in the hypertension induced by the VEGFR-2 kinase inhibitors axitinib and lenvatinib in conscious freely-moving rats.
Biochem Pharmacol
; : 116007, 2023 Dec 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38145828
12.
Involvement of ß-adrenoceptors in the cardiovascular responses induced by selective adenosine A2A and A2B receptor agonists.
Pharmacol Res Perspect
; 10(3): e00975, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35643970
13.
Monitoring haemodynamic changes in rodent models to better inform safety pharmacology: Novel insights from in vivo studies and waveform analysis.
JRSM Cardiovasc Dis
; 11: 20480040221092893, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35646334
14.
Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis.
J Biol Chem
; 285(8): 5532-40, 2010 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-19906640
15.
Use of NanoBiT and NanoBRET to monitor fluorescent VEGF-A binding kinetics to VEGFR2/NRP1 heteromeric complexes in living cells.
Br J Pharmacol
; 178(12): 2393-2411, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33655497
16.
Subtype selective fluorescent ligands based on ICI 118,551 to study the human ß2-adrenoceptor in CRISPR/Cas9 genome-edited HEK293T cells at low expression levels.
Pharmacol Res Perspect
; 9(3): e00779, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34003582
17.
NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization.
SLAS Discov
; 25(2): 186-194, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31583945
18.
Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies.
Cell Chem Biol
; 27(10): 1250-1261.e5, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32610042
19.
The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats.
Br J Pharmacol
; 177(2): 346-359, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31596949
20.
Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells.
Commun Biol
; 3(1): 722, 2020 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33247190