Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Eur J Nutr ; 55(8): 2365-2376, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26410392

RESUMO

PURPOSE: A phytochemical- and mineral-rich filtered sugarcane molasses concentrate (FMC), when added to carbohydrate-containing foods as a functional ingredient, lowers postprandial blood glucose and insulin responses. We hypothesised that this beneficial effect would also occur if FMC was administered as an oral supplement taken before a meal. METHODS: This study measured the postprandial glucose and insulin responses elicited by different doses of FMC administered immediately prior to a standard breakfast to healthy subjects. Each subject was given three or five breakfast meals once, on different days. The composition of the meals was identical, except for the addition of either placebo syrup (test meal 1) or increasing doses of FMC (test meals 2-5). RESULTS: The plasma glucose concentration curves were similar for the five test meals. Plasma insulin curves were lowered in a dose-dependent manner. Stratifying subjects based on age, BMI and insulin resistance showed greater effects of low doses of FMC on lowering insulin responses in those subjects with potentially greater insulin resistance. When insulin response is standardised to amount of carbohydrate in the meal/dose combination, the reduction in response is linear and inversely proportional to the FMC dose. CONCLUSIONS: FMC shows promise as an agent that can reduce insulin responses and lessen the load on the pancreatic beta cells.


Assuntos
Insulina/sangue , Melaço/análise , Período Pós-Prandial , Saccharum/química , Adolescente , Adulto , Glicemia/metabolismo , Índice de Massa Corporal , Desjejum , Estudos Cross-Over , Carboidratos da Dieta/administração & dosagem , Carboidratos da Dieta/análise , Gorduras na Dieta/administração & dosagem , Gorduras na Dieta/análise , Fibras na Dieta/administração & dosagem , Fibras na Dieta/análise , Proteínas Alimentares/administração & dosagem , Proteínas Alimentares/análise , Relação Dose-Resposta a Droga , Ingestão de Energia , Feminino , Humanos , Resistência à Insulina , Células Secretoras de Insulina/efeitos dos fármacos , Células Secretoras de Insulina/metabolismo , Masculino , Micronutrientes/administração & dosagem , Micronutrientes/análise , Compostos Fitoquímicos/administração & dosagem , Compostos Fitoquímicos/análise , Método Simples-Cego , Adulto Jovem
2.
Plant Foods Hum Nutr ; 69(4): 310-6, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25373842

RESUMO

An aqueous filtered molasses concentrate (FMC) sourced from sugar cane was used as a functional ingredient in a range of carbohydrate-containing foods to reduce glycaemic response. When compared to untreated controls, postprandial glucose responses in the test products were reduced 5-20%, assessed by accredited glycaemic index (GI) testing. The reduction in glucose response in the test foods was dose-dependent and directly proportional to the ratio of FMC added to the amount of available carbohydrate in the test products. The insulin response to the foods was also reduced with FMC addition as compared to untreated controls. Inclusion of FMC in test foods did not replace any formulation ingredients; it was incorporated as an additional ingredient to existing formulations. Filtered molasses concentrate, made by a proprietary and patented process, contains many naturally occurring compounds. Some of the identified compounds are known to influence carbohydrate metabolism, and include phenolic compounds, minerals and organic acids. FMC, sourced from a by-product of sugar cane processing, shows potential as a natural functional ingredient capable of modifying carbohydrate metabolism and contributing to GI reduction of processed foods and beverages.


Assuntos
Glicemia/metabolismo , Dieta , Carboidratos da Dieta/metabolismo , Índice Glicêmico , Insulina/metabolismo , Melaço , Saccharum , Adolescente , Adulto , Alimento Funcional , Humanos , Período Pós-Prandial , Saccharum/química , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa