Detalhe da pesquisa
1.
Fast and Inexpensive Detection of Bacterial Viability and Drug Effectiveness through Metabolic Monitoring.
Sensors (Basel)
; 16(11)2016 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27834850
2.
An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.
J Biol Chem
; 289(9): 5809-19, 2014 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24366873
3.
Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.
Proc Natl Acad Sci U S A
; 109(47): 19368-73, 2012 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-23134728
4.
An integrated array of microfluidic oxygenators as a neonatal lung assist device: in vitro characterization and in vivo demonstration.
Artif Organs
; 38(10): 856-66, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24716531
5.
A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation.
Cancer Discov
; 2024 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38691346
6.
SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy.
Cancer Discov
; 13(8): 1789-1801, 2023 08 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37269335
7.
Discovery and SAR of spirochromane Akt inhibitors.
Bioorg Med Chem Lett
; 21(8): 2410-4, 2011 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21392984
8.
Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA.
Bioorg Med Chem Lett
; 21(8): 2335-40, 2011 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21420856
9.
Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors.
Bioorg Med Chem Lett
; 20(23): 7037-41, 2010 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20971641
10.
Lipid phosphate phosphatases from Saccharomyces cerevisiae.
Methods Enzymol
; 434: 305-15, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17954255
11.
A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.
Cancer Discov
; 7(9): 963-972, 2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28578312
12.
Fluid Dynamics and Biofilm Removal Generated by Syringe-delivered and 2 Ultrasonic-assisted Irrigation Methods: A Novel Experimental Approach.
J Endod
; 41(6): 884-9, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25749254
13.
Artificial placenta--lung assist devices for term and preterm newborns with respiratory failure.
Int J Artif Organs
; 36(6): 377-91, 2013 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-23645582
14.
Lung assist device: development of microfluidic oxygenators for preterm infants with respiratory failure.
Lab Chip
; 13(13): 2641-50, 2013 Jul 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23702615
15.
Polyurethane-based microfluidic devices for blood contacting applications.
Lab Chip
; 12(5): 960-70, 2012 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22273592
16.
An ATP-site on-off switch that restricts phosphatase accessibility of Akt.
Sci Signal
; 5(223): ra37, 2012 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22569334
17.
Transport of particles and microorganisms in microfluidic channels using rectified ac electro-osmotic flow.
Biomicrofluidics
; 5(1): 13407, 2011 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-21522497
18.
Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
ACS Med Chem Lett
; 2(5): 342-7, 2011 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24900315
19.
Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition.
PLoS One
; 5(9): e12913, 2010 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-20886116
20.
The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme.
J Biol Chem
; 281(14): 9210-8, 2006 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-16467296