Detalhe da pesquisa
1.
Toward simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients.
Drug Dev Ind Pharm
; 46(12): 2051-2060, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33124918
2.
Montmorillonite-surfactant hybrid particles for modulating intestinal P-glycoprotein-mediated transport.
Int J Pharm
; 571: 118696, 2019 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31525443
3.
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).
J Med Chem
; 51(4): 875-96, 2008 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-18254606
4.
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship.
J Med Chem
; 50(19): 4572-84, 2007 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17722899
5.
New model for intravenous drug administration and blood sampling in the awake rat, designed to increase quality and throughput for in vivo pharmacokinetic analysis.
J Pharmacol Toxicol Methods
; 52(2): 293-301, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-16125629
6.
In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor.
J Control Release
; 199: 1-9, 2015 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25485732
7.
Blood microsampling using capillaries for drug-exposure determination in early preclinical studies: a beneficial strategy to reduce blood sample volumes.
Bioanalysis
; 6(3): 293-306, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24471951
8.
Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery.
Clin Pharmacokinet
; 50(8): 505-17, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21740074