Detalhe da pesquisa
1.
Actinomycin D enhances killing of cancer cells by immunotoxin RG7787 through activation of the extrinsic pathway of apoptosis.
Proc Natl Acad Sci U S A
; 113(38): 10666-71, 2016 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27601652
2.
Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.
Proc Natl Acad Sci U S A
; 109(18): 6898-903, 2012 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22509046
3.
Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes.
Proc Natl Acad Sci U S A
; 109(29): 11782-7, 2012 Jul 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22753489
4.
A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene.
J Biol Chem
; 288(17): 12305-12, 2013 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-23486472
5.
Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.
Proc Natl Acad Sci U S A
; 108(14): 5742-7, 2011 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21436054
6.
Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts.
J Biol Chem
; 286(31): 27761-8, 2011 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21669876
7.
A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
Blood
; 113(16): 3792-800, 2009 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-18988862
8.
An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.
Proc Natl Acad Sci U S A
; 105(32): 11311-6, 2008 Aug 12.
Artigo
Inglês
| MEDLINE | ID: mdl-18678888
9.
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
Clin Cancer Res
; 12(15): 4695-701, 2006 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16899620
10.
Immunoglobulin superfamily receptor translocation associated 2 protein on lymphoma cell lines and hairy cell leukemia cells detected by novel monoclonal antibodies.
Clin Cancer Res
; 11(1): 87-96, 2005 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15671532
11.
Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide.
Nucleic Acids Res
; 32(5): e48, 2004 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-15026537
12.
Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity.
Oncotarget
; 7(21): 29916-26, 2016 May 24.
Artigo
Inglês
| MEDLINE | ID: mdl-27167198
13.
Mesothelin Expression in Advanced Gastroesophageal Cancer Represents a Novel Target for Immunotherapy.
Appl Immunohistochem Mol Morphol
; 24(4): 246-52, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26894650
14.
Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.
Mol Cancer Ther
; 1(5): 337-46, 2002 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12489850
15.
Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors.
Mol Cancer Ther
; 14(12): 2789-96, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26443804
16.
Self-assembly of a virus-mimicking nanostructure system for efficient tumor-targeted gene delivery.
Hum Gene Ther
; 13(3): 469-81, 2002 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-11860713
17.
Antitumor effects of immunotoxins are enhanced by lowering HCK or treatment with SRC kinase inhibitors.
Mol Cancer Ther
; 13(1): 82-9, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24145282
18.
Efficacy of RG7787, a next-generation mesothelin-targeted immunotoxin, against triple-negative breast and gastric cancers.
Mol Cancer Ther
; 13(11): 2653-61, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25239937
19.
A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity.
Mol Cancer Ther
; 12(1): 48-57, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23136186
20.
Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia cell line KOPN-8.
Leuk Res
; 37(11): 1551-6, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24070652