Detalhe da pesquisa
1.
A double-hit in vivo model of GBA viral microRNA-mediated downregulation and human alpha-synuclein overexpression demonstrates nigrostriatal degeneration.
Neurobiol Dis
; 163: 105612, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34995756
2.
Psychosis-Like Behavior and Hyperdopaminergic Dysregulation in Human α-Synuclein BAC Transgenic Rats.
Mov Disord
; 36(3): 716-728, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33200461
3.
Neurons and Glia Interplay in α-Synucleinopathies.
Int J Mol Sci
; 22(9)2021 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34066733
4.
Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins.
Mol Cell Neurosci
; 95: 1-12, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30562574
5.
Correction to: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models.
Acta Neuropathol
; 138(4): 675, 2019 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-31485733
6.
Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models.
Acta Neuropathol
; 138(3): 415-441, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31011860
7.
Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies.
Mov Disord
; 31(2): 178-92, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26813776
8.
Chaperone mediated autophagy to the rescue: A new-fangled target for the treatment of neurodegenerative diseases.
Mol Cell Neurosci
; 66(Pt A): 29-36, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25724482
9.
Lysosomal alterations in peripheral blood mononuclear cells of Parkinson's disease patients.
Mov Disord
; 30(13): 1830-4, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26769460
10.
The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro.
Neurobiol Dis
; 63: 1-11, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24269733
11.
Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system.
Hum Mol Genet
; 21(4): 874-89, 2012 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22076440
12.
Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.
Brain
; 136(Pt 7): 2130-46, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23757764
13.
MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology.
iScience
; 26(11): 108100, 2023 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37915594
14.
Exosomes in Alpha-Synucleinopathies: Propagators of Pathology or Potential Candidates for Nanotherapeutics?
Biomolecules
; 12(7)2022 07 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35883513
15.
Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models.
Autophagy
; 18(9): 2104-2133, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35000546
16.
Coordinated activation of TGF-ß and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication.
Sci Signal
; 15(740): eabn4395, 2022 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35763560
17.
Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein.
Commun Biol
; 5(1): 1040, 2022 09 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36180728
18.
High content screening and proteomic analysis identify a kinase inhibitor that rescues pathological phenotypes in a patient-derived model of Parkinson's disease.
NPJ Parkinsons Dis
; 8(1): 15, 2022 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35149677
19.
Autophagic pathways in Parkinson disease and related disorders.
Expert Rev Mol Med
; 13: e8, 2011 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21418705
20.
Correction: Loss of ß-Glucocerebrosidase Activity Does Not Affect Alpha-Synuclein Levels or Lysosomal Function in Neuronal Cells.
PLoS One
; 16(6): e0252975, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34086800