Detalhe da pesquisa
1.
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance.
Immunity
; 54(5): 931-946.e11, 2021 05 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33838102
2.
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Mol Cell
; 82(13): 2472-2489.e8, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35537449
3.
Muscle-derived Dpp regulates feeding initiation via endocrine modulation of brain dopamine biosynthesis.
Genes Dev
; 34(1-2): 37-52, 2020 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31831628
4.
A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription.
EMBO J
; 41(6): e108544, 2022 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34850409
5.
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.
Blood
; 143(7): 619-630, 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37890156
6.
THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration.
Nucleic Acids Res
; 52(6): 3291-3309, 2024 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38165050
7.
Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens.
Proc Natl Acad Sci U S A
; 120(16): e2220134120, 2023 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37036970
8.
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.
Nature
; 565(7737): 101-105, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30568299
9.
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Nature
; 576(7787): 471-476, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31827283
10.
ABCC4 impacts megakaryopoiesis and protects megakaryocytes against 6-mercaptopurine induced cytotoxicity.
Drug Resist Updat
; 72: 101017, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37988981
11.
The genetic basis and cell of origin of mixed phenotype acute leukaemia.
Nature
; 562(7727): 373-379, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30209392
12.
FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis.
Blood
; 137(2): 155-167, 2021 01 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33156908
13.
Genomic profiling identifies genes and pathways dysregulated by HEY1-NCOA2 fusion and shines a light on mesenchymal chondrosarcoma tumorigenesis.
J Pathol
; 257(5): 579-592, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35342947
14.
Orthotopic patient-derived xenografts of paediatric solid tumours.
Nature
; 549(7670): 96-100, 2017 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28854174
15.
The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.
Genes Dev
; 29(23): 2475-89, 2015 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26584623
16.
Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs.
EMBO Rep
; 21(8): e50095, 2020 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32558197
17.
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping.
Nucleic Acids Res
; 47(13): 6699-6713, 2019 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31127282
18.
Complex sex-biased antibody responses: estrogen receptors bind estrogen response elements centered within immunoglobulin heavy chain gene enhancers.
Int Immunol
; 31(3): 141-156, 2019 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30407507
19.
Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease.
Cell Immunol
; 346: 103996, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31703914
20.
Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
Acta Neuropathol
; 137(6): 1021, 2019 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-30976974