Pesquisa | Secretaria de Estado da Saúde

1.

Bat pluripotent stem cells reveal unusual entanglement between host and viruses.

Déjosez, Marion; Marin, Arturo; Hughes, Graham M; Morales, Ariadna E; Godoy-Parejo, Carlos; Gray, Jonathan L; Qin, Yiren; Singh, Arun A; Xu, Hui; Juste, Javier; Ibáñez, Carlos; White, Kris M; Rosales, Romel; Francoeur, Nancy J; Sebra, Robert P; Alcock, Dominic; Volkert, Thomas L; Puechmaille, Sébastien J; Pastusiak, Andrzej; Frost, Simon D W; Hiller, Michael; Young, Richard A; Teeling, Emma C; García-Sastre, Adolfo; Zwaka, Thomas P.

Cell ; 186(5): 957-974.e28, 2023 03 02.

Artigo Inglês | MEDLINE | ID: mdl-36812912

2.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Xu, Hui; Li, Tianbo; Rohou, Alexis; Arthur, Christopher P; Tzakoniati, Foteini; Wong, Evera; Estevez, Alberto; Kugel, Christine; Franke, Yvonne; Chen, Jun; Ciferri, Claudio; Hackos, David H; Koth, Christopher M; Payandeh, Jian.

Cell ; 176(4): 702-715.e14, 2019 02 07.

Artigo Inglês | MEDLINE | ID: mdl-30661758

3.

Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.

Cooper, Lucy; Xu, Hui; Polmear, Jack; Kealy, Liam; Szeto, Christopher; Pang, Ee Shan; Gupta, Mansi; Kirn, Alana; Taylor, Justin J; Jackson, Katherine J L; Broomfield, Benjamin J; Nguyen, Angela; Gago da Graça, Catarina; La Gruta, Nicole; Utzschneider, Daniel T; Groom, Joanna R; Martelotto, Luciano; Parish, Ian A; O'Keeffe, Meredith; Scharer, Christopher D; Gras, Stephanie; Good-Jacobson, Kim L.

Immunity ; 57(5): 1037-1055.e6, 2024 May 14.

Artigo Inglês | MEDLINE | ID: mdl-38593796

4.

Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.

Cai, Xin; Chen, Jueqi; Xu, Hui; Liu, Siqi; Jiang, Qiu-Xing; Halfmann, Randal; Chen, Zhijian J.

Cell ; 156(6): 1207-1222, 2014 Mar 13.

Artigo Inglês | MEDLINE | ID: mdl-24630723

5.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Xu, Hui; Li, Tianbo; Rohou, Alexis; Arthur, Christopher P; Tzakoniati, Foteini; Wong, Evera; Estevez, Alberto; Kugel, Christine; Franke, Yvonne; Chen, Jun; Ciferri, Claudio; Hackos, David H; Koth, Christopher M; Payandeh, Jian.

Cell ; 176(5): 1238-1239, 2019 Feb 21.

Artigo Inglês | MEDLINE | ID: mdl-30794776

6.

Lanthanide-doped inorganic nanoparticles turn molecular triplet excitons bright.

Han, Sanyang; Deng, Renren; Gu, Qifei; Ni, Limeng; Huynh, Uyen; Zhang, Jiangbin; Yi, Zhigao; Zhao, Baodan; Tamura, Hiroyuki; Pershin, Anton; Xu, Hui; Huang, Zhiyuan; Ahmad, Shahab; Abdi-Jalebi, Mojtaba; Sadhanala, Aditya; Tang, Ming Lee; Bakulin, Artem; Beljonne, David; Liu, Xiaogang; Rao, Akshay.

Nature ; 587(7835): 594-599, 2020 11.

Artigo Inglês | MEDLINE | ID: mdl-33239799

7.

Apoptotic Vesicular Metabolism Contributes to Organelle Assembly and Safeguards Liver Homeostasis and Regeneration.

Sui, Bingdong; Wang, Runci; Chen, Chider; Kou, Xiaoxing; Wu, Di; Fu, Yu; Lei, Fangcao; Wang, Yanzhuang; Liu, Yijing; Chen, Xiaoyuan; Xu, Hui; Liu, Yingying; Kang, Junjun; Liu, Haixiang; Kwok, Ryan Tsz Kin; Tang, Ben Zhong; Yan, Hexin; Wang, Minjun; Xiang, Lei; Yan, Xutong; Zhang, Xiao; Ma, Lan; Shi, Songtao; Jin, Yan.

Gastroenterology ; 2024 Feb 10.

Artigo Inglês | MEDLINE | ID: mdl-38342194

8.

Brain microvascular endothelial cell-derived exosomes transmitting circ_0000495 promote microglial M1-polarization and endothelial cell injury under hypoxia condition.

Min, Xiao-Li; Jia, Wen-Ji; Guo, Li; Jing, Rui; Zhao, Xiao-Hong; Hu, Jia-Yi; Li, Xu-Hui; Liu, Wei; Wang, Tao; Dou, Xing-Kui.

FASEB J ; 38(2): e23387, 2024 01 31.

Artigo Inglês | MEDLINE | ID: mdl-38193649

9.

Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice.

Li, Yong-Xia; Tan, Zhi-Nei; Li, Xu-Hui; Ma, Boyu; Adu Nti, Frank; Lv, Xiao-Qiang; Tian, Zhen-Jun; Yan, Riqiang; Man, Heng-Ye; Ma, Xin-Ming.

Mol Psychiatry ; 2024 Mar 19.

Artigo Inglês | MEDLINE | ID: mdl-38503925

10.

Botulinum toxin type a blocks aquaporin 5 trafficking by decreasing synaptosomal-associated protein 23 in submandibular acinar cells.

Xu, Hui; Ge, Huabing; Cai, Zhigang.

Exp Cell Res ; 436(2): 113954, 2024 Mar 15.

Artigo Inglês | MEDLINE | ID: mdl-38307188

11.

FliL ring enhances the function of periplasmic flagella.

Guo, Shuaiqi; Xu, Hui; Chang, Yunjie; Motaleb, Md A; Liu, Jun.

Proc Natl Acad Sci U S A ; 119(11): e2117245119, 2022 03 15.

Artigo Inglês | MEDLINE | ID: mdl-35254893

12.

Visual pigment-deficient cones survive and mediate visual signaling despite the lack of outer segments.

Xu, Hui; Jin, Nange; Chuang, Jen-Zen; Zhang, Zhao; Zhong, Xiaoyue; Zhang, Zhijing; Sung, Ching-Hwa; Ribelayga, Christophe P; Fu, Yingbin.

Proc Natl Acad Sci U S A ; 119(9)2022 03 01.

Artigo Inglês | MEDLINE | ID: mdl-35197287

13.

Mitochondrial GPAT-derived LPA controls auxin-dependent embryonic and postembryonic development.

Jia, Qianru; Bai, Yang; Xu, Hui; Liu, Qingyun; Li, Wenyan; Li, Teng; Lin, Feng; Shen, Like; Xuan, Wei; Zhang, Wenhua; Zhang, Qun.

Proc Natl Acad Sci U S A ; 119(49): e2212881119, 2022 12 06.

Artigo Inglês | MEDLINE | ID: mdl-36454754

14.

Single-cell RNA sequencing integrated with bulk RNA sequencing analysis identifies a tumor immune microenvironment-related lncRNA signature in lung adenocarcinoma.

Ren, Yuqing; Wu, Ruhao; Li, Chunwei; Liu, Long; Li, Lifeng; Weng, Siyuan; Xu, Hui; Xing, Zhe; Zhang, Yuyuan; Wang, Libo; Liu, Zaoqu; Han, Xinwei.

BMC Biol ; 22(1): 69, 2024 Mar 22.

Artigo Inglês | MEDLINE | ID: mdl-38519942

15.

Using two self-developed InDel panels to explore forensic traits and ancestral components in the Hui group.

Yuan, Xi; Wang, Xi; Lan, Qiong; Li, Shuanglin; Lin, Yifeng; Zhao, Ming; Xu, Hui; Lei, Fanzhang; Shen, Chunmei; Zhu, Bofeng.

Genomics ; 116(1): 110756, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-38061479

16.

Soft Actuator with Biomass Porous Electrode: A Strategy for Lowering Voltage and Enhancing Durability.

Zhang, Hao; Ma, Suqian; Xu, Chuhan; Ma, Jiayao; Chen, Yan; Hu, Yong; Xu, Hui; Lin, Zhaohua; Liang, Yunhong; Ren, Lei; Ren, Luquan.

Nano Lett ; 2024 Apr 09.

Artigo Inglês | MEDLINE | ID: mdl-38592087

17.

Integrated Exploration of Epigenetic Dysregulation Reveals a Stemness/EMT Subtype and MMP12 Linked to the Progression and Prognosis in Hepatocellular Carcinoma.

Zuo, Anning; Li, Jinyu; Weng, Siyuan; Xu, Hui; Zhang, Yuyuan; Wang, Libo; Xing, Zhe; Luo, Peng; Cheng, Quan; Li, Jing; Han, Xinwei; Liu, Zaoqu.

J Proteome Res ; 23(5): 1821-1833, 2024 May 03.

Artigo Inglês | MEDLINE | ID: mdl-38652053

18.

Cellular Ligand-Receptor Perturbations Unravel MEIS2 as a Key Factor for the Aggressive Progression and Prognosis in Stage II/III Colorectal Cancer.

Xu, Hui; Chen, Shuang; Li, Jing; Weng, Siyuan; Ren, Yuqing; Zhang, Yuyuan; Wang, Libo; Liu, Long; Guo, Chunguang; Xing, Zhe; Luo, Peng; Cheng, Quan; Han, Xinwei; Liu, Zaoqu.

J Proteome Res ; 23(2): 760-774, 2024 Feb 02.

Artigo Inglês | MEDLINE | ID: mdl-38153233

19.

Molecular basis of Q-length selectivity for the MW1 antibody-huntingtin interaction.

Bravo-Arredondo, Jose M; Venkataraman, Rajashree; Varkey, Jobin; Isas, Jose Mario; Situ, Alan J; Xu, Hui; Chen, Jeannie; Ulmer, Tobias S; Langen, Ralf.

J Biol Chem ; 299(4): 104616, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36931390

20.

KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter.

Yuan, Xiaofan; Jiang, Chuan; Xue, Yuzhou; Guo, Fuqiang; Luo, Minghao; Guo, Lei; Gao, Yang; Yuan, Tongling; Xu, Hui; Chen, Hong.

J Cell Physiol ; 239(5): e31251, 2024 May.

Artigo Inglês | MEDLINE | ID: mdl-38634445

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Bat pluripotent stem cells reveal unusual entanglement between host and viruses.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.

Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Lanthanide-doped inorganic nanoparticles turn molecular triplet excitons bright.

Apoptotic Vesicular Metabolism Contributes to Organelle Assembly and Safeguards Liver Homeostasis and Regeneration.

Brain microvascular endothelial cell-derived exosomes transmitting circ_0000495 promote microglial M1-polarization and endothelial cell injury under hypoxia condition.

Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice.

Botulinum toxin type a blocks aquaporin 5 trafficking by decreasing synaptosomal-associated protein 23 in submandibular acinar cells.

FliL ring enhances the function of periplasmic flagella.

Visual pigment-deficient cones survive and mediate visual signaling despite the lack of outer segments.

Mitochondrial GPAT-derived LPA controls auxin-dependent embryonic and postembryonic development.

Single-cell RNA sequencing integrated with bulk RNA sequencing analysis identifies a tumor immune microenvironment-related lncRNA signature in lung adenocarcinoma.

Using two self-developed InDel panels to explore forensic traits and ancestral components in the Hui group.

Soft Actuator with Biomass Porous Electrode: A Strategy for Lowering Voltage and Enhancing Durability.

Integrated Exploration of Epigenetic Dysregulation Reveals a Stemness/EMT Subtype and MMP12 Linked to the Progression and Prognosis in Hepatocellular Carcinoma.

Cellular Ligand-Receptor Perturbations Unravel MEIS2 as a Key Factor for the Aggressive Progression and Prognosis in Stage II/III Colorectal Cancer.

Molecular basis of Q-length selectivity for the MW1 antibody-huntingtin interaction.

KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter.