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BACKGROUND: Accurate pesticide inline mixing uniformity (PIMU) evaluation for direct nozzle injection systems (DNIS) helps evaluate system performance and develop efficient inline mixers. Based on supervised machine learning (ML), inline mixing images and computational fluid dynamics (CFD) simulations are directly associated for realizing intelligent PIMU predictions. RESULTS: Image sets can be reduced to less than 3% of the data size at the same time as retaining 98% of information using principal component analysis (PCA). The CFD results, as referenced values for ML, were justified by mixture sampling experiments. Enhanced images for the long-mixing tube effectively trained models including generalized linear model (GLM), support vector regression (SVR), BP-neural network (NNW), and classification and regression trees (CART). By testing the re-collected images, the verification accuracy of GLM was less than 95% and it failed to recognize uniformity differences under varying working conditions, whereas NNW, CART and SVR realized it with an accuracy for NNW and CART higher than 97% and for SVR slightly lower than 97%. By testing images of the jet mixer, the prediction accuracy compared with the CFD results of NNW and CART was also higher than 97%, although that for SVR was relatively lower, and insignificant declines in accuracy were observed on comparing the results with mixture sampling experiments. CONCLUSION: PCA facilitates evaluations of CFD-referenced PIMU using image-based ML. Models trained by enhanced image sets of the long-mixing tube have satisfactory performance. NNW and CART performed slightly better than SVR, and they can be used as tools to improve the rationality when evaluating PIMU in DNIS. © 2022 Society of Chemical Industry.
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Praguicidas , Aprendizado de Máquina , Simulação por Computador , Hidrodinâmica , Redes Neurais de ComputaçãoRESUMO
The stability of slope is critical important topic in rock mass engineering. In Panzhihua #7 Coal Mine, the coal mining is occurred under the slope, to obtain the optimal mining width, 125 numerical simulations were conducted, and the corresponding FOS was calculated. From the analysis of the numerical simulation results, it can be found that FOS decrease and then increase with increasing of filling length, meanwhile, the FOS is minimum value when the filling length is within the ranges of 10 m and 20 m, which is under the toe of slope. Furthermore, the minimum FOS decrease with increasing of mining width. Considered the stability of the slope and mining economy, the mining width is set to 6m, and the numerical simulation results is applied to the engineering practice. To guarantee the safety of the slope, some monitoring points were distributed on the slope, the displacement from numerical simulation and engineering practice is quite close, indicating the numerical simulation results is reliable, and the mining width is reasonable.
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The compaction characteristics and bearing capacity of dry filling materials in goaf have a significant influence on stope control and surface stability. Through acoustic emission monitoring and mechanical model analysis, a series of confined compression tests were conducted on crushed waste with varying particle sizes and Talbot coefficients. The deformation, fragmentation, and acoustic emission characteristics under corresponding working conditions were determined. The results indicate that the stress-strain curves of crushed stone with different particle sizes and Talbot coefficients exhibit similar nonlinear behavior during confined compression. However, the strain response varies with changing stress levels. By analyzing the slope change rate of the stress-strain curve, the lateral uniaxial compression process of waste rock can be divided into three deformation stages: rapid compression, stable crushing, and slow compaction. The compressive deformation characteristics of gravel differ based on particle size and Talbot coefficient. Specimens with a higher Talbot coefficient demonstrate stronger compressive resistance and weaker deformation resistance during initial compaction loading. Notably, the internal pressure structure strength is influenced by factors such as maximum particle size D, grading coefficient n, and particle size distribution continuity, rather than solely by the proportion of large particles. The evolution of acoustic emission signals and energy-time curve during waste rock confined axial compression synchronizes with the compaction process. Overall, compaction plays a critical role in maintaining the stability of goaf in dry crushed waste filling.
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To comprehensively analyze the effect of cutting parameters on the 3D surface topography of machined potassium dihydrogen phosphate crystals, 2D power spectrum density and continuous wavelet transform are used to extract and reconstruct the arbitrary actual 3D frequency features of machined potassium dihydrogen phosphate crystal surfaces. The 2D power spectrum density method is used to quantitatively describe the 3D surface topography of machined potassium dihydrogen phosphate crystals. The continuous wavelet transform method is applied to extract and reconstruct 3D topographies of arbitrary actual spatial frequency features in machined surfaces. The main spatial frequency features fx of the machined surfaces are 0.0056 µm-1, 0.0112 µm-1, and 0.0277 µm-1 with the cutting depth from 3 µm to 9 µm. With the feed rate changing from 8µm/r to 18 µm/r, the main spatial frequency features fx are 0.0056 µm-1-0.0277 µm-1. With the spindle speed from 1300 r/min to 1500 r/min, the main spatial frequency features fx are same as the main spatial frequency features of the cutting depths. The results indicate that the variation of cutting parameters affects the main spatial frequency features on the 3D surface topography. The amplitudes of the spatial middle-frequency features are increased with the increasing of cutting depth and spindle speed. The spatial low-frequency features are mainly affected via the feed rate. The spatial high-frequency features are related to the measurement noise and material properties of potassium dihydrogen phosphate. The distributional directions of the frequency features in the reconstructed 3D surface topography are consistent with the distribution directions of actual frequency features in the original surface topography. The reconstructed topographies of the spatial frequency features with maximum power spectrum density are the most similar to the original 3D surfaces. In this machining, the best 3D surface topography of the machined KDP crystals is obtained with a cutting depth ap = 3 µm, feed rate f = 8 µm/r and a spindle speed n = 1400 r/min.
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The use of active suspension for vehicle height adjustment has problems of high cost, high energy consumption, slow response, and complex structure. This paper proposes a new method for adjusting the vehicle body using the damping asymmetric characteristic of semi-active suspensions, which is based on the idea that the dampers with damping asymmetric characteristics will cause a change in the mean position of the vehicle body vibration. To verify the feasibility of this method, a single-wheel vehicle model containing asymmetric damping is established. The system's responses under the sinusoidal and random roads excitation are obtained by the fourth-order Runge-Kutta method, the influences of key parameters on the vehicle body's shifting height are analyzed, and the mechanism of vehicle body's shift is explained from the perspective of energy conservation. Then a vehicle body height controller based on third-order linear active disturbance rejection control (LADRC) is designed. Simulation results show that the proposed method for controlling the vehicle height with asymmetric damping can quickly adjust the vehicle to the expected height whether under the sinusoidal road or random road. In addition, no additional hardware and energy consumption are required, providing a new idea for vehicle height control.
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Vibração , Simulação por ComputadorRESUMO
To determine the Gurson-Tvergaard-Needleman (GTN)damage model parameters of 6061 aluminum alloy after secondary heat treatment, the uniaxial tensile test was carried out on the aluminum alloy circular arc specimen, and the mechanical properties parameters and the load-displacement curve of aluminum alloy tube were obtained. With the help of the finite element reverse method, scanning electron microscope and a orthogonal test method, the GTN damage model parameters (f0, fN, fC, and fF) were calibrated, and their values were 0.004535, 0.04, 0.1, and 0.2135, respectively. Then the shear specimen and notch specimen were designed to verify the damage model, the results show that the obtained GTN damage model parameters can effectively predict the fracture failure of 6061 aluminum alloy after secondary heat treatment during the tensile process.
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One of the most challenging safety problems is ground instability during crossing overlying remnant pillars (CORP). Ground instability not only causes injury to miners or fatalities, but also leads to interruptions in the mining operations and breakdowns in equipment. In this paper, 12 major parameters influencing the ground instability were firstly determined based on extensive international experience associated with CORP. The consequences of the ground instability were then assessed in terms of miners' health and financial losses. Afterwards, a practical method to assess the ground instability risk of lower-seam longwall panels during CORP was developed based on its probability and consequence. Finally, this method was successfully used to determine the best scheme for CORP of LW10-103 at Mugua coal mine. The main advantage of this method is that it enables mining engineers to easily use international experience for assessing the risk of ground instability and selecting reasonable supports during CORP.
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The present study aimed to identify differentially regulated genes between the peritumoral brain zone (PBZ) and tumor core (TC) of glioblastoma (GBM), to elucidate the underlying molecular mechanisms and provide a target for the treatment of tumors. The GSE13276 and GSE116520 datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) for the PBZ and TC were obtained using the GEO2R tool. The bioinformatics and evolutionary genomics online tool Venn was used to identify common DEGs between the two datasets. The Database for Annotation, Visualization, and Integrated Discovery online tool was used to analyze enriched pathways of the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. The Search Tool for the Retrieval of Interacting Genes/Proteins online tool was used to construct a protein-protein interaction (PPI) network of DEGs. Hub genes were identified using Cytohubba, a plug-in for Cytoscape. The Gene Expression Profiling Interactive Analysis (GEPIA) database was utilized to perform survival analysis. In total, 75 DEGs, including 12 upregulated and 63 downregulated genes, were identified. In the GO term analysis, these DEGs were mainly enriched in 'regulation of angiogenesis' and 'central nervous system development'. Furthermore, in the KEGG pathway analysis, the DEGs were mainly enriched in 'bladder cancer' and 'endocytosis'. When filtering the results of the PPI network analysis using Cytohubba, a total of 10 hub genes, including proteolipid protein 1, myelin associated oligodendrocyte basic protein, contactin 2, myelin oligodendrocyte glycoprotein, myelin basic protein, myelin associated glycoprotein, SRY-box transcription factor 10, C-X-C motif chemokine ligand 8 (CXCL8), vascular endothelial growth factor A (VEGFA) and plasmolipin, were identified. These hub genes were further subjected to GO term and KEGG pathway analysis, and were revealed to be enriched in 'central nervous system development', 'bladder cancer' and 'rheumatoid arthritis'. These hub genes were used to perform survival analysis using the GEPIA database, and it was determined that VEGFA and CXCL8 were significantly associated with a reduction in the overall survival of patients with GBM. In conclusion, the results suggest that the recurrence of GBM is associated with high gene expression levels VEGFA and CXCL8, and the development of the central nervous system.
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Maglev, offers competitive journey-times compared to the railway and subway systems in markets for which distance between the stations is 100-1600km owing to its high acceleration and speed; however, such systems may have excessive vibration. Field measurements of Maglev train-induced vibrations were therefore performed on the world's first commercial Maglev line in Shanghai, China. Seven test sections along the line were selected according to the operating conditions, covering speeds from 150 to 430km/h. Acceleration responses of bridge pier and nearby ground were measured in three directions and analyzed in both the time and frequency domain. The effects of Maglev train speed on vibrations of the bridge pier and ground were studied in terms of their peak accelerations. Attenuation of ground vibration was investigated up to 30m from the track centerline. Effects of guideway configuration were also analyzed based on the measurements through two different test sections with same train speed of 300km/h. The results showed that peak accelerations exhibited a strong correlation with both train speed and distance off the track. Guideway configuration had a significant effect on transverse vibration, but a weak impact on vertical and longitudinal vibrations of both bridge pier and ground. Statistics indicated that, contrary to the commonly accepted theory and experience, vertical vibration is not always dominant: transverse and longitudinal vibrations should also be considered, particularly near turns in the track. Moreover, measurements of ground vibration induced by traditional high-speed railway train were carried out with the same testing devices in Bengbu in the Anhui Province. Results showed that the Maglev train generates significantly different vibration signatures as compared to the traditional high-speed train. The results obtained from this paper can provide good insights on the impact of Maglev system on the urban environment and the quality of human life nearby.