Detalhe da pesquisa
1.
Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.
FASEB J
; 33(9): 10240-10256, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31211923
2.
Effect of methoxyflavones contained in Kaempferia parviflora on CRE-mediated transcription in PC12D cells.
Bioorg Med Chem Lett
; 30(23): 127606, 2020 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33038547
3.
Tyrosine hydroxylase gene expression is facilitated by alcohol followed by the degradation of the protein by ubiquitin proteasome system.
Neuro Endocrinol Lett
; 38(1): 43-49, 2017 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-28456147
4.
Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system.
Biochem Biophys Res Commun
; 465(1): 53-8, 2015 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-26225746
5.
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice.
Neurobiol Aging
; 139: 20-29, 2024 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-38583392
6.
Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition.
PLoS Biol
; 8(7): e1000416, 2010 Jul 06.
Artigo
Inglês
| MEDLINE | ID: mdl-20625546
7.
Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action.
J Neural Transm (Vienna)
; 120(10): 1397-409, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23588349
8.
Nobiletin induces inhibitions of Ras activity and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells.
Biol Pharm Bull
; 36(4): 540-7, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23546290
9.
New myrsinol diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production.
Bioorg Med Chem Lett
; 22(11): 3612-8, 2012 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22560584
10.
Isolation, structural elucidation, and neuroprotective effects of iridoids from Valeriana jatamansi.
Biosci Biotechnol Biochem
; 76(7): 1401-3, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22785467
11.
Honeybee royal jelly and nobiletin stimulate CRE-mediated transcription in ERK-independent and -dependent fashions, respectively, in PC12D cells.
J Pharmacol Sci
; 116(4): 384-7, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21747212
12.
High-performance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound.
Anal Bioanal Chem
; 400(10): 3635-41, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21559759
13.
Neuroprotective Kaurane Diterpenes from Fritillaria ebeiensis.
Biosci Biotechnol Biochem
; 75(7): 1386-8, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21737919
14.
Dual effects of nobiletin, a citrus polymethoxy flavone, on catecholamine secretion in cultured bovine adrenal medullary cells.
J Neurochem
; 114(4): 1030-8, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20533991
15.
[Preventive action of nobiletin, a constituent of AURANTII NOBILIS PERICARPIUM with anti-dementia activity, against amyloid-beta peptide-induced neurotoxicity expression and memory impairment].
Yakugaku Zasshi
; 130(4): 517-20, 2010 Apr.
Artigo
Japonês
| MEDLINE | ID: mdl-20371995
16.
4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
Biochemistry
; 48(32): 7713-21, 2009 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-19601643
17.
Nobiletin, a citrus flavonoid, improves memory impairment and Abeta pathology in a transgenic mouse model of Alzheimer's disease.
J Pharmacol Exp Ther
; 326(3): 739-44, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-18544674
18.
Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.
Eur J Pharmacol
; 578(2-3): 194-200, 2008 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-17976577
19.
Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance catecholamine synthesis and its nicotine-evoked elevation in PC12D cells.
Toxicology
; 394: 84-92, 2018 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29246838
20.
A novel mechanism of depression: role for connexins.
Eur Neuropsychopharmacol
; 28(4): 483-498, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29519610